| 2018 |
Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.
|
Oncotarget |
Horn, M., Kroef, V., Allmeroth, K., Schuller, N., Miethe, S., Peifer, M., Penninger, JM., Elling, U., Denzel, MS. |
| 2017 |
DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.
|
Cell Stem Cell |
Choi, J., Clement, K., Huebner, AJ., Webster, J., Rose, CM., Brumbaugh, J., Walsh, RM., Lee, S., Savol, A., Etchegaray, JP., Gu, H., Boyle, P., Elling, U., Mostoslavsky, R., Sadreyev, R., Park, PJ., Gygi, SP., Meissner, A., Hochedlinger, K. |
| 2017 |
A vital sugar code for ricin toxicity.
|
Cell Res |
Taubenschmid, J., Stadlmann, J., Jost, M., Klokk, TI., Rillahan, CD., Leibbrandt, A., Mechtler, K., Paulson, JC., Jude, J., Zuber, J., Sandvig, K., Elling, U., Marquardt, T., Thiel, C., Koerner, C., Penninger, JM. |
| 2017 |
Comparative glycoproteomics of stem cells identifies new players in ricin toxicity.
|
Nature |
Stadlmann, J., Taubenschmid, J., Wenzel, D., Gattinger, A., Dürnberger, G., Dusberger, F., Elling, U., Mach, L., Mechtler, K., Penninger, JM. |
| 2017 |
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
|
Nature |
Elling, U., Wimmer, RA., Leibbrandt, A., Burkard, T., Michlits, G., Leopoldi, A., Micheler, T., Abdeen, D., Zhuk, S., Aspalter, IM., Handl, C., Liebergesell, J., Hubmann, M., Husa, AM., Kinzer, M., Schuller, N., Wetzel, E., van de Loo, N., Martinez, JAZ., Estoppey, D., Riedl, R., Yang, F., Fu, B., Dechat, T., Ivics, Z., Agu, CA., Bell, O., Blaas, D., Gerhardt, H., Hoepfner, D., Stark, A., Penninger, JM. |
| 2017 |
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
|
Nat Methods |
Michlits, G., Hubmann, M., Wu, SH., Vainorius, G., Budusan, E., Zhuk, S., Burkard, TR., Novatchkova, M., Aichinger, M., Lu, Y., Reece-Hoyes, J., Nitsch, R., Schramek, D., Hoepfner, D., Elling, U. |
| 2016 |
Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.
|
Development |
Breuss, M., Fritz, T., Gstrein, T., Chan, K., Ushakova, L., Yu, N., Vonberg, FW., Werner, B., Elling, U., Keays, DA. |
| 2016 |
The mevalonate pathway regulates primitive streak formation via protein farnesylation.
|
Sci Rep |
Okamoto-Uchida, Y., Yu, R., Miyamura, N., Arima, N., Ishigami-Yuasa, M., Kagechika, H., Yoshida, S., Hosoya, T., Nawa, M., Kasama, T., Asaoka, Y., Alois, RW., Elling, U., Penninger, JM., Nishina, S., Azuma, N., Nishina, H. |
| 2015 |
The histone chaperone CAF-1 safeguards somatic cell identity.
|
Nature |
Cheloufi, S., Elling, U., Hopfgartner, B., Jung, YL., Murn, J., Ninova, M., Hubmann, M., Badeaux, AI., Euong Ang, C., Tenen, D., Wesche, DJ., Abazova, N., Hogue, M., Tasdemir, N., Brumbaugh, J., Rathert, P., Jude, J., Ferrari, F., Blanco, A., Fellner, M., Wenzel, D., Zinner, M., Vidal, SE., Bell, O., Stadtfeld, M., Chang, HY., Almouzni, G., Lowe, SW., Rinn, J., Wernig, M., Aravin, A., Shi, Y., Park, PJ., Penninger, JM., Zuber, J., Hochedlinger, K. |
| 2014 |
Genome wide functional genetics in haploid cells.
|
FEBS Lett |
Elling, U., Penninger, JM. |
| 2014 |
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.
|
Nat Genet |
Wirnsberger, G., Zwolanek, F., Stadlmann, J., Tortola, L., Liu, SW., Perlot, T., Järvinen, P., Dürnberger, G., Kozieradzki, I., Sarao, R., De Martino, A., Boztug, K., Mechtler, K., Kuchler, K., Klein, C., Elling, U., Penninger, JM. |
| 2014 |
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia.
|
Nat Genet |
Boztug, K., Järvinen, PM., Salzer, E., Racek, T., Mönch, S., Garncarz, W., Gertz, EM., Schäffer, AA., Antonopoulos, A., Haslam, SM., Schieck, L., Pucha?ka, J., Diestelhorst, J., Appaswamy, G., Lescoeur, B., Giambruno, R., Bigenzahn, JW., Elling, U., Pfeifer, D., Conde, CD., Albert, MH., Welte, K., Brandes, G., Sherkat, R., van der Werff Ten Bosch, J., Rezaei, N., Etzioni, A., Bellanné-Chantelot, C., Superti-Furga, G., Penninger, JM., Bennett, KL., von Blume, J., Dell, A., Donadieu, J., Klein, C. |
| 2012 |
Seventy-five genetic loci influencing the human red blood cell.
|
Nature |
van der Harst, P., Zhang, W., Mateo Leach, I., Rendon, A., Verweij, N., Sehmi, J., Paul, DS., Elling, U., Allayee, H., Li, X., Radhakrishnan, A., Tan, ST., Voss, K., Weichenberger, CX., Albers, CA., Al-Hussani, A., Asselbergs, FW., Ciullo, M., Danjou, F., Dina, C., Esko, T., Evans, DM., Franke, L., Gögele, M., Hartiala, J., Hersch, M., Holm, H., Hottenga, JJ., Kanoni, S., Kleber, ME., Lagou, V., Langenberg, C., Lopez, LM., Lyytikäinen, LP., Melander, O., Murgia, F., Nolte, IM., O'Reilly, PF., Padmanabhan, S., Parsa, A., Pirastu, N., Porcu, E., Portas, L., Prokopenko, I., Ried, JS., Shin, SY., Tang, CS., Teumer, A., Traglia, M., Ulivi, S., Westra, HJ., Yang, J., Zhao, JH., Anni, F., Abdellaoui, A., Attwood, A., Balkau, B., Bandinelli, S., Bastardot, F., Benyamin, B., Boehm, BO., Cookson, WO., Das, D., de Bakker, PI., de Boer, RA., de Geus, EJ., de Moor, MH., Dimitriou, M., Domingues, FS., Döring, A., Engström, G., Eyjolfsson, GI., Ferrucci, L., Fischer, K., Galanello, R., Garner, SF., Genser, B., Gibson, QD., Girotto, G., Gudbjartsson, DF., Harris, SE., Hartikainen, AL., Hastie, CE., Hedblad, B., Illig, T., Jolley, J., Kähönen, M., Kema, IP., Kemp, JP., Liang, L., Lloyd-Jones, H., Loos, RJ., Meacham, S., Medland, SE., Meisinger, C., Memari, Y., Mihailov, E., Miller, K., Moffatt, MF., Nauck, M., Novatchkova, M., Nutile, T., Olafsson, I., Onundarson, PT., Parracciani, D., Penninx, BW., Perseu, L., Piga, A., Pistis, G., Pouta, A., Puc, U., Raitakari, O., Ring, SM., Robino, A., Ruggiero, D., Ruokonen, A., Saint-Pierre, A., Sala, C., Salumets, A., Sambrook, J., Schepers, H., Schmidt, CO., Silljé, HH., Sladek, R., Smit, JH., Starr, JM., Stephens, J., Sulem, P., Tanaka, T., Thorsteinsdottir, U., Tragante, V., van Gilst, WH., van Pelt, LJ., van Veldhuisen, DJ., Völker, U., Whitfield, JB., Willemsen, G., Winkelmann, BR., Wirnsberger, G., Algra, A., Cucca, F., d'Adamo, AP., Danesh, J., Deary, IJ., Dominiczak, AF., Elliott, P., Fortina, P., Froguel, P., Gasparini, P., Greinacher, A., Hazen, SL., Jarvelin, MR., Khaw, KT., Lehtimäki, T., Maerz, W., Martin, NG., Metspalu, A., Mitchell, BD., Montgomery, GW., Moore, C., Navis, G., Pirastu, M., Pramstaller, PP., Ramirez-Solis, R., Schadt, E., Scott, J., Shuldiner, AR., Smith, GD., Smith, JG., Snieder, H., Sorice, R., Spector, TD., Stefansson, K., Stumvoll, M., Tang, WH., Toniolo, D., Tönjes, A., Visscher, PM., Vollenweider, P., Wareham, NJ., Wolffenbuttel, BH., Boomsma, DI., Beckmann, JS., Dedoussis, GV., Deloukas, P., Ferreira, MA., Sanna, S., Uda, M., Hicks, AA., Penninger, JM., Gieger, C., Kooner, JS., Ouwehand, WH., Soranzo, N., Chambers, JC. |
| 2011 |
The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression.
|
Nat Genet |
Schramek, D., Kotsinas, A., Meixner, A., Wada, T., Elling, U., Pospisilik, JA., Neely, GG., Zwick, RH., Sigl, V., Forni, G., Serrano, M., Gorgoulis, VG., Penninger, JM. |
| 2011 |
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.
|
Cell Stem Cell |
Elling, U., Taubenschmid, J., Wirnsberger, G., O'Malley, R., Demers, SP., Vanhaelen, Q., Shukalyuk, AI., Schmauss, G., Schramek, D., Schnuetgen, F., von Melchner, H., Ecker, JR., Stanford, WL., Zuber, J., Stark, A., Penninger, JM. |
| 2011 |
New gene functions in megakaryopoiesis and platelet formation.
|
Nature |
Gieger, C., Radhakrishnan, A., Cvejic, A., Tang, W., Porcu, E., Pistis, G., Serbanovic-Canic, J., Elling, U., Goodall, AH., Labrune, Y., Lopez, LM., Mägi, R., Meacham, S., Okada, Y., Pirastu, N., Sorice, R., Teumer, A., Voss, K., Zhang, W., Ramirez-Solis, R., Bis, JC., Ellinghaus, D., Gögele, M., Hottenga, JJ., Langenberg, C., Kovacs, P., O'Reilly, PF., Shin, SY., Esko, T., Hartiala, J., Kanoni, S., Murgia, F., Parsa, A., Stephens, J., van der Harst, P., Ellen van der Schoot, C., Allayee, H., Attwood, A., Balkau, B., Bastardot, F., Basu, S., Baumeister, SE., Biino, G., Bomba, L., Bonnefond, A., Cambien, F., Chambers, JC., Cucca, F., D'Adamo, P., Davies, G., de Boer, RA., de Geus, EJ., Döring, A., Elliott, P., Erdmann, J., Evans, DM., Falchi, M., Feng, W., Folsom, AR., Frazer, IH., Gibson, QD., Glazer, NL., Hammond, C., Hartikainen, AL., Heckbert, SR., Hengstenberg, C., Hersch, M., Illig, T., Loos, RJ., Jolley, J., Khaw, KT., Kühnel, B., Kyrtsonis, MC., Lagou, V., Lloyd-Jones, H., Lumley, T., Mangino, M., Maschio, A., Mateo Leach, I., McKnight, B., Memari, Y., Mitchell, BD., Montgomery, GW., Nakamura, Y., Nauck, M., Navis, G., Nöthlings, U., Nolte, IM., Porteous, DJ., Pouta, A., Pramstaller, PP., Pullat, J., Ring, SM., Rotter, JI., Ruggiero, D., Ruokonen, A., Sala, C., Samani, NJ., Sambrook, J., Schlessinger, D., Schreiber, S., Schunkert, H., Scott, J., Smith, NL., Snieder, H., Starr, JM., Stumvoll, M., Takahashi, A., Tang, WH., Taylor, K., Tenesa, A., Lay Thein, S., Tönjes, A., Uda, M., Ulivi, S., van Veldhuisen, DJ., Visscher, PM., Völker, U., Wichmann, HE., Wiggins, KL., Willemsen, G., Yang, TP., Hua Zhao, J., Zitting, P., Bradley, JR., Dedoussis, GV., Gasparini, P., Hazen, SL., Metspalu, A., Pirastu, M., Shuldiner, AR., Joost van Pelt, L., Zwaginga, JJ., Boomsma, DI., Deary, IJ., Franke, A., Froguel, P., Ganesh, SK., Jarvelin, MR., Martin, NG., Meisinger, C., Psaty, BM., Spector, TD., Wareham, NJ., Akkerman, JW., Ciullo, M., Deloukas, P., Greinacher, A., Jupe, S., Kamatani, N., Khadake, J., Kooner, JS., Penninger, J., Prokopenko, I., Stemple, D., Toniolo, D., Wernisch, L., Sanna, S., Hicks, AA., Rendon, A., Ferreira, MA., Ouwehand, WH., Soranzo, N. |
| 2010 |
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
|
Cell |
Neely, GG., Kuba, K., Cammarato, A., Isobe, K., Amann, S., Zhang, L., Murata, M., Elmén, L., Gupta, V., Arora, S., Sarangi, R., Dan, D., Fujisawa, S., Usami, T., Xia, CP., Keene, AC., Alayari, NN., Yamakawa, H., Elling, U., Berger, C., Novatchkova, M., Koglgruber, R., Fukuda, K., Nishina, H., Isobe, M., Pospisilik, JA., Imai, Y., Pfeufer, A., Hicks, AA., Pramstaller, PP., Subramaniam, S., Kimura, A., Ocorr, K., Bodmer, R., Penninger, JM. |
| 2006 |
Murine inner cell mass-derived lineages depend on Sall4 function.
|
Proc Natl Acad Sci U S A |
Elling, U., Klasen, C., Eisenberger, T., Anlag, K., Treier, M. |
| 2002 |
Roles of the Homothorax/Meis/Prep homolog UNC-62 and the Exd/Pbx homologs CEH-20 and CEH-40 in C. elegans embryogenesis.
|
Development |
Van Auken, K., Weaver, D., Robertson, B., Sundaram, M., Saldi, T., Edgar, L., Elling, U., Lee, M., Boese, Q., Wood, WB. |
