| 2019 |
The novel lncRNA <i>lnc-NR2F1</i> is pro-neurogenic and mutated in human neurodevelopmental disorders.
|
Elife |
Ang, CE., Ma, Q., Wapinski, OL., Fan, S., Flynn, RA., Lee, QY., Coe, B., Onoguchi, M., Olmos, VH., Do, BT., Dukes-Rimsky, L., Xu, J., Tanabe, K., Wang, L., Elling, U., Penninger, JM., Zhao, Y., Qu, K., Eichler, EE., Srivastava, A., Wernig, M., Chang, HY. |
| 2019 |
Using Functional Genetics in Haploid Cells for Drug Target Identification.
|
Methods Mol Biol |
Volz, JC., Schuller, N., Elling, U. |
| 2019 |
Derivation and maintenance of mouse haploid embryonic stem cells.
|
Nat Protoc |
Elling, U., Woods, M., Forment, JV., Fu, B., Yang, F., Ng, BL., Vicente, JR., Adams, DJ., Doe, B., Jackson, SP., Penninger, JM., Balmus, G. |
| 2019 |
Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing.
|
Nat Commun |
Moussa, HF., Bsteh, D., Yelagandula, R., Pribitzer, C., Stecher, K., Bartalska, K., Michetti, L., Wang, J., Zepeda-Martinez, JA., Elling, U., Stuckey, JI., James, LI., Frye, SV., Bell, O. |
| 2019 |
CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.
|
Nat Commun |
Chylinski, K., Hubmann, M., Hanna, RE., Yanchus, C., Michlits, G., Uijttewaal, ECH., Doench, J., Schramek, D., Elling, U. |
| 2018 |
Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.
|
Hum Genet |
Stephen, J., Nampoothiri, S., Banerjee, A., Tolman, NJ., Penninger, JM., Elling, U., Agu, CA., Burke, JD., Devadathan, K., Kannan, R., Huang, Y., Steinbach, PJ., Martinis, SA., Gahl, WA., Malicdan, MCV. |
| 2018 |
Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.
|
Cell Stem Cell |
Mor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., Elinger, D., Viukov, S., Geula, S., Krupalnik, V., Zerbib, M., Chomsky, E., Lasman, L., Shani, T., Bayerl, J., Gafni, O., Hanna, S., Buenrostro, JD., Hagai, T., Masika, H., Vainorius, G., Bergman, Y., Greenleaf, WJ., Esteban, MA., Elling, U., Levin, Y., Massarwa, R., Merbl, Y., Novershtern, N., Hanna, JH. |
| 2018 |
Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.
|
Oncotarget |
Horn, M., Kroef, V., Allmeroth, K., Schuller, N., Miethe, S., Peifer, M., Penninger, JM., Elling, U., Denzel, MS. |
| 2017 |
Comparative glycoproteomics of stem cells identifies new players in ricin toxicity.
|
Nature |
Stadlmann, J., Taubenschmid, J., Wenzel, D., Gattinger, A., Dürnberger, G., Dusberger, F., Elling, U., Mach, L., Mechtler, K., Penninger, JM. |
| 2017 |
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
|
Nature |
Elling, U., Wimmer, RA., Leibbrandt, A., Burkard, T., Michlits, G., Leopoldi, A., Micheler, T., Abdeen, D., Zhuk, S., Aspalter, IM., Handl, C., Liebergesell, J., Hubmann, M., Husa, AM., Kinzer, M., Schuller, N., Wetzel, E., van de Loo, N., Martinez, JAZ., Estoppey, D., Riedl, R., Yang, F., Fu, B., Dechat, T., Ivics, Z., Agu, CA., Bell, O., Blaas, D., Gerhardt, H., Hoepfner, D., Stark, A., Penninger, JM. |
| 2017 |
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
|
Nat Methods |
Michlits, G., Hubmann, M., Wu, SH., Vainorius, G., Budusan, E., Zhuk, S., Burkard, TR., Novatchkova, M., Aichinger, M., Lu, Y., Reece-Hoyes, J., Nitsch, R., Schramek, D., Hoepfner, D., Elling, U. |
| 2017 |
DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.
|
Cell Stem Cell |
Choi, J., Clement, K., Huebner, AJ., Webster, J., Rose, CM., Brumbaugh, J., Walsh, RM., Lee, S., Savol, A., Etchegaray, JP., Gu, H., Boyle, P., Elling, U., Mostoslavsky, R., Sadreyev, R., Park, PJ., Gygi, SP., Meissner, A., Hochedlinger, K. |
| 2017 |
A vital sugar code for ricin toxicity.
|
Cell Res |
Taubenschmid, J., Stadlmann, J., Jost, M., Klokk, TI., Rillahan, CD., Leibbrandt, A., Mechtler, K., Paulson, JC., Jude, J., Zuber, J., Sandvig, K., Elling, U., Marquardt, T., Thiel, C., Koerner, C., Penninger, JM. |
| 2016 |
Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.
|
Development |
Breuss, M., Fritz, T., Gstrein, T., Chan, K., Ushakova, L., Yu, N., Vonberg, FW., Werner, B., Elling, U., Keays, DA. |
| 2016 |
The mevalonate pathway regulates primitive streak formation via protein farnesylation.
|
Sci Rep |
Okamoto-Uchida, Y., Yu, R., Miyamura, N., Arima, N., Ishigami-Yuasa, M., Kagechika, H., Yoshida, S., Hosoya, T., Nawa, M., Kasama, T., Asaoka, Y., Alois, RW., Elling, U., Penninger, JM., Nishina, S., Azuma, N., Nishina, H. |
| 2015 |
The histone chaperone CAF-1 safeguards somatic cell identity.
|
Nature |
Cheloufi, S., Elling, U., Hopfgartner, B., Jung, YL., Murn, J., Ninova, M., Hubmann, M., Badeaux, AI., Euong Ang, C., Tenen, D., Wesche, DJ., Abazova, N., Hogue, M., Tasdemir, N., Brumbaugh, J., Rathert, P., Jude, J., Ferrari, F., Blanco, A., Fellner, M., Wenzel, D., Zinner, M., Vidal, SE., Bell, O., Stadtfeld, M., Chang, HY., Almouzni, G., Lowe, SW., Rinn, J., Wernig, M., Aravin, A., Shi, Y., Park, PJ., Penninger, JM., Zuber, J., Hochedlinger, K. |
| 2014 |
Genome wide functional genetics in haploid cells.
|
FEBS Lett |
Elling, U., Penninger, JM. |
| 2014 |
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.
|
Nat Genet |
Wirnsberger, G., Zwolanek, F., Stadlmann, J., Tortola, L., Liu, SW., Perlot, T., Järvinen, P., Dürnberger, G., Kozieradzki, I., Sarao, R., De Martino, A., Boztug, K., Mechtler, K., Kuchler, K., Klein, C., Elling, U., Penninger, JM. |
| 2014 |
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia.
|
Nat Genet |
Boztug, K., Järvinen, PM., Salzer, E., Racek, T., Mönch, S., Garncarz, W., Gertz, EM., Schäffer, AA., Antonopoulos, A., Haslam, SM., Schieck, L., Puchałka, J., Diestelhorst, J., Appaswamy, G., Lescoeur, B., Giambruno, R., Bigenzahn, JW., Elling, U., Pfeifer, D., Conde, CD., Albert, MH., Welte, K., Brandes, G., Sherkat, R., van der Werff Ten Bosch, J., Rezaei, N., Etzioni, A., Bellanné-Chantelot, C., Superti-Furga, G., Penninger, JM., Bennett, KL., von Blume, J., Dell, A., Donadieu, J., Klein, C. |
| 2012 |
Seventy-five genetic loci influencing the human red blood cell.
|
Nature |
van der Harst, P., Zhang, W., Mateo Leach, I., Rendon, A., Verweij, N., Sehmi, J., Paul, DS., Elling, U., Allayee, H., Li, X., Radhakrishnan, A., Tan, ST., Voss, K., Weichenberger, CX., Albers, CA., Al-Hussani, A., Asselbergs, FW., Ciullo, M., Danjou, F., Dina, C., Esko, T., Evans, DM., Franke, L., Gögele, M., Hartiala, J., Hersch, M., Holm, H., Hottenga, JJ., Kanoni, S., Kleber, ME., Lagou, V., Langenberg, C., Lopez, LM., Lyytikäinen, LP., Melander, O., Murgia, F., Nolte, IM., O'Reilly, PF., Padmanabhan, S., Parsa, A., Pirastu, N., Porcu, E., Portas, L., Prokopenko, I., Ried, JS., Shin, SY., Tang, CS., Teumer, A., Traglia, M., Ulivi, S., Westra, HJ., Yang, J., Zhao, JH., Anni, F., Abdellaoui, A., Attwood, A., Balkau, B., Bandinelli, S., Bastardot, F., Benyamin, B., Boehm, BO., Cookson, WO., Das, D., de Bakker, PI., de Boer, RA., de Geus, EJ., de Moor, MH., Dimitriou, M., Domingues, FS., Döring, A., Engström, G., Eyjolfsson, GI., Ferrucci, L., Fischer, K., Galanello, R., Garner, SF., Genser, B., Gibson, QD., Girotto, G., Gudbjartsson, DF., Harris, SE., Hartikainen, AL., Hastie, CE., Hedblad, B., Illig, T., Jolley, J., Kähönen, M., Kema, IP., Kemp, JP., Liang, L., Lloyd-Jones, H., Loos, RJ., Meacham, S., Medland, SE., Meisinger, C., Memari, Y., Mihailov, E., Miller, K., Moffatt, MF., Nauck, M., Novatchkova, M., Nutile, T., Olafsson, I., Onundarson, PT., Parracciani, D., Penninx, BW., Perseu, L., Piga, A., Pistis, G., Pouta, A., Puc, U., Raitakari, O., Ring, SM., Robino, A., Ruggiero, D., Ruokonen, A., Saint-Pierre, A., Sala, C., Salumets, A., Sambrook, J., Schepers, H., Schmidt, CO., Silljé, HH., Sladek, R., Smit, JH., Starr, JM., Stephens, J., Sulem, P., Tanaka, T., Thorsteinsdottir, U., Tragante, V., van Gilst, WH., van Pelt, LJ., van Veldhuisen, DJ., Völker, U., Whitfield, JB., Willemsen, G., Winkelmann, BR., Wirnsberger, G., Algra, A., Cucca, F., d'Adamo, AP., Danesh, J., Deary, IJ., Dominiczak, AF., Elliott, P., Fortina, P., Froguel, P., Gasparini, P., Greinacher, A., Hazen, SL., Jarvelin, MR., Khaw, KT., Lehtimäki, T., Maerz, W., Martin, NG., Metspalu, A., Mitchell, BD., Montgomery, GW., Moore, C., Navis, G., Pirastu, M., Pramstaller, PP., Ramirez-Solis, R., Schadt, E., Scott, J., Shuldiner, AR., Smith, GD., Smith, JG., Snieder, H., Sorice, R., Spector, TD., Stefansson, K., Stumvoll, M., Tang, WH., Toniolo, D., Tönjes, A., Visscher, PM., Vollenweider, P., Wareham, NJ., Wolffenbuttel, BH., Boomsma, DI., Beckmann, JS., Dedoussis, GV., Deloukas, P., Ferreira, MA., Sanna, S., Uda, M., Hicks, AA., Penninger, JM., Gieger, C., Kooner, JS., Ouwehand, WH., Soranzo, N., Chambers, JC. |
