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Publications

Year Title Journal Authors
2017 A heterochromatin-dependent transcription machinery drives piRNA expression. Nature Andersen, PR., Tirian, L., Vunjak, M., Brennecke, J.
2016 Genetic and mechanistic diversity of piRNA 3'-end formation. Nature Hayashi, R., Schnabl, J., Handler, D., Mohn, F., Ameres, SL., Brennecke, J.
2015 piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire. Genes Dev Senti, KA., Jurczak, D., Sachidanandam, R., Brennecke, J.
2015 Silencio/CG9754 connects the Piwi-piRNA complex to the cellular heterochromatin machinery. Genes Dev Sienski, G., Batki, J., Senti, KA., Dönertas, D., Tirian, L., Meixner, K., Brennecke, J.
2015 Noncoding RNA. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis. Science Mohn, F., Handler, D., Brennecke, J.
2015 Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified. Dev Cell Marinov, GK., Wang, J., Handler, D., Wold, BJ., Weng, Z., Hannon, GJ., Aravin, AA., Zamore, PD., Brennecke, J., Toth, KF.
2014 The exon junction complex is required for definition and excision of neighboring introns in Drosophila. Genes Dev Hayashi, R., Handler, D., Ish-Horowicz, D., Brennecke, J.
2014 The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila. Cell Mohn, F., Sienski, G., Handler, D., Brennecke, J.
2013 Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex. Genes Dev Dönertas, D., Sienski, G., Brennecke, J.
2013 The genetic makeup of the Drosophila piRNA pathway. Mol Cell Handler, D., Meixner, K., Pizka, M., Lauss, K., Schmied, C., Gruber, FS., Brennecke, J.
2012 Preparation of small RNA libraries for high-throughput sequencing. Cold Spring Harb Protoc Malone, C., Brennecke, J., Czech, B., Aravin, A., Hannon, GJ.
2012 Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression. Cell Sienski, G., Dönertas, D., Brennecke, J.
2012 The cochaperone shutdown defines a group of biogenesis factors essential for all piRNA populations in Drosophila. Mol Cell Olivieri, D., Senti, KA., Subramanian, S., Sachidanandam, R., Brennecke, J.
2011 A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nat Methods Ni, JQ., Zhou, R., Czech, B., Liu, LP., Holderbaum, L., Yang-Zhou, D., Shim, HS., Tao, R., Handler, D., Karpowicz, P., Binari, R., Booker, M., Brennecke, J., Perkins, LA., Hannon, GJ., Perrimon, N.
2011 A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. EMBO J Handler, D., Olivieri, D., Novatchkova, M., Gruber, FS., Meixner, K., Mechtler, K., Stark, A., Sachidanandam, R., Brennecke, J.
2010 An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila. EMBO J Olivieri, D., Sykora, MM., Sachidanandam, R., Mechtler, K., Brennecke, J.
2010 The piRNA pathway: a fly's perspective on the guardian of the genome. Trends Genet Senti, KA., Brennecke, J.
2009 Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell Malone, CD., Brennecke, J., Dus, M., Stark, A., McCombie, WR., Sachidanandam, R., Hannon, GJ.
2009 Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA Zhou, R., Czech, B., Brennecke, J., Sachidanandam, R., Wohlschlegel, JA., Perrimon, N., Hannon, GJ.
2009 Hierarchical rules for Argonaute loading in Drosophila. Mol Cell Czech, B., Zhou, R., Erlich, Y., Brennecke, J., Binari, R., Villalta, C., Gordon, A., Perrimon, N., Hannon, GJ.