Publications

Search Publications

Year	Title	Journal	Authors
2021	A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.	J Exp Med	Hagelkruys, A., Wirnsberger, G., Stadlmann, J., Wöhner, M., Horrer, M., Vilagos, B., Jonsson, G., Kogler, M., Tortola, L., Novatchkova, M., Bönelt, P., Hoffmann, D., Koglgruber, R., Steffen, U., Schett, G., Busslinger, M., Bergthaler, A., Klein, C., Penninger, JM.
2020	Human recombinant soluble ACE2 in severe COVID-19.	Lancet Respir Med	Zoufaly, A., Poglitsch, M., Aberle, JH., Hoepler, W., Seitz, T., Traugott, M., Grieb, A., Pawelka, E., Laferl, H., Wenisch, C., Neuhold, S., Haider, D., Stiasny, K., Bergthaler, A., Puchhammer-Stoeckl, E., Mirazimi, A., Montserrat, N., Zhang, H., Slutsky, AS., Penninger, JM.
2020	Fibroblasts as a source of self-antigens for central immune tolerance.	Nat Immunol	Nitta, T., Tsutsumi, M., Nitta, S., Muro, R., Suzuki, EC., Nakano, K., Tomofuji, Y., Sawa, S., Okamura, T., Penninger, JM., Takayanagi, H.
2020	Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1 K/K Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung for Inflation at Birth.	Front Bioeng Biotechnol	Szoták-Ajtay, K., Szõke, D., Kovács, G., Andréka, J., Brenner, GB., Giricz, Z., Penninger, J., Kahn, ML., Jakus, Z.
2020	The Role of Angiotensin Converting Enzyme 2 (ACE2) in Modulating Gut Microbiota, Intestinal Inflammation, and Coronavirus Infection.	Gastroenterology	Penninger, JM., Grant, MB., Sung, JJY.
2020	Targeting the RANKL/RANK/OPG Axis for Cancer Therapy.	Front Oncol	Ming, J., Cronin, SJF., Penninger, JM.
2020	CLP1 acts as the main RNA kinase in mice.	Biochem Biophys Res Commun	Fujinami, H., Shiraishi, H., Hada, K., Inoue, M., Morisaki, I., Higa, R., Shin, T., Kobayashi, T., Hanada, R., Penninger, JM., Mimata, H., Hanada, T.
2020	JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.	Sci Adv	Stebbing, J., Sánchez Nievas, G., Falcone, M., Youhanna, S., Richardson, P., Ottaviani, S., Shen, JX., Sommerauer, C., Tiseo, G., Ghiadoni, L., Virdis, A., Monzani, F., Rizos, LR., Forfori, F., Avendaño-Céspedes, A., De Marco, S., Carrozzi, L., Lena, F., Sánchez-Jurado, PM., Lacerenza, LG., Cesira, N., Caldevilla-Bernardo, D., Perrella, A., Niccoli, L., Méndez, LS., Matarrese, D., Goletti, D., Tan, YJ., Monteil, V., Dranitsaris, G., Cantini, F., Farcomeni, A., Dutta, S., Burley, SK., Zhang, H., Pistello, M., Li, W., Mas Romero, M., Andrés Pretel, F., Simón-Talero, RS., García-Molina, R., Kutter, C., Felce, JH., Nizami, ZF., Miklosi, AG., Penninger, JM., Menichetti, F., Mirazimi, A., Abizanda, P., Lauschke, VM.
2020	B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction.	Nat Commun	Minato, T., Nirasawa, S., Sato, T., Yamaguchi, T., Hoshizaki, M., Inagaki, T., Nakahara, K., Yoshihashi, T., Ozawa, R., Yokota, S., Natsui, M., Koyota, S., Yoshiya, T., Yoshizawa-Kumagaye, K., Motoyama, S., Gotoh, T., Nakaoka, Y., Penninger, JM., Watanabe, H., Imai, Y., Takahashi, S., Kuba, K.
2020	Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.	Cell Death Dis	Li, T., Li, K., Zhang, S., Wang, Y., Xu, Y., Cronin, SJF., Sun, Y., Zhang, Y., Xie, C., Rodriguez, J., Zhou, K., Hagberg, H., Mallard, C., Wang, X., Penninger, JM., Kroemer, G., Blomgren, K., Zhu, C.
2020	Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.	Intensive Care Med	Zhang, H., Penninger, JM., Li, Y., Zhong, N., Slutsky, AS.
2020	Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury.	FASEB J	Bravo-Caparrós, I., Ruiz-Cantero, MC., Perazzoli, G., Cronin, SJF., Vela, JM., Hamed, MF., Penninger, JM., Baeyens, JM., Cobos, EJ., Nieto, FR.
2020	RANKL and OPG and their influence on breast volume changes during pregnancy in healthy women.	Sci Rep	Wunderle, M., Ruebner, M., Häberle, L., Schwenke, E., Hack, CC., Bayer, CM., Koch, MC., Schwitulla, J., Schulz-Wendtland, R., Kozieradzki, I., Lux, MP., Beckmann, MW., Jud, SM., Penninger, JM., Schneider, MO., Fasching, PA.
2020	Correction: The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes.	PLoS Genet	Andergassen, D., Muckenhuber, M., Bammer, PC., Kulinski, TM., Theussl, HC., Shimizu, T., Penninger, JM., Pauler, FM., Hudson, QJ.
2020	Salmonella-based platform for efficient delivery of functional binding proteins to the cytosol.	Commun Biol	Chabloz, A., Schaefer, JV., Kozieradzki, I., Cronin, SJF., Strebinger, D., Macaluso, F., Wald, J., Rabbitts, TH., Plückthun, A., Marlovits, TC., Penninger, JM.
2020	HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases.	Cancer Res	Kogler, M., Tortola, L., Negri, GL., Leopoldi, A., El-Naggar, AM., Mereiter, S., Gomez Diaz, C., Nitsch, R., Tortora, D., Kavirayani, AM., Gapp, BV., Rao, S., Uribesalgo, I., Hoffmann, D., Cikes, D., Novatchkova, M., Williams, DA., Trent, JM., Ikeda, F., Daugaard, M., Hagelkruys, A., Sorensen, PH., Penninger, JM.
2020	Identification of ALK in Thinness.	Cell	Orthofer, M., Valsesia, A., Mägi, R., Wang, QP., Kaczanowska, J., Kozieradzki, I., Leopoldi, A., Cikes, D., Zopf, LM., Tretiakov, EO., Demetz, E., Hilbe, R., Boehm, A., Ticevic, M., Nõukas, M., Jais, A., Spirk, K., Clark, T., Amann, S., Lepamets, M., Neumayr, C., Arnold, C., Dou, Z., Kuhn, V., Novatchkova, M., Cronin, SJF., Tietge, UJF., Müller, S., Pospisilik, JA., Nagy, V., Hui, CC., Lazovic, J., Esterbauer, H., Hagelkruys, A., Tancevski, I., Kiefer, FW., Harkany, T., Haubensak, W., Neely, GG., Metspalu, A., Hager, J., Gheldof, N., Penninger, JM.
2020	Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.	Cell	Monteil, V., Kwon, H., Prado, P., Hagelkrüys, A., Wimmer, RA., Stahl, M., Leopoldi, A., Garreta, E., Hurtado Del Pozo, C., Prosper, F., Romero, JP., Wirnsberger, G., Zhang, H., Slutsky, AS., Conder, R., Montserrat, N., Mirazimi, A., Penninger, JM.
2020	Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.	Emerg Microbes Infect	Appelberg, S., Gupta, S., Svensson Akusjärvi, S., Ambikan, AT., Mikaeloff, F., Saccon, E., Végvári, Á., Benfeitas, R., Sperk, M., Ståhlberg, M., Krishnan, S., Singh, K., Penninger, JM., Mirazimi, A., Neogi, U.
2020	Sclerostin expression in trabecular bone is downregulated by osteoclasts.	Sci Rep	Koide, M., Yamashita, T., Murakami, K., Uehara, S., Nakamura, K., Nakamura, M., Matsushita, M., Ara, T., Yasuda, H., Penninger, JM., Takahashi, N., Udagawa, N., Kobayashi, Y.