| 2021 |
A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.
|
J Exp Med |
Hagelkruys, A., Wirnsberger, G., Stadlmann, J., Wöhner, M., Horrer, M., Vilagos, B., Jonsson, G., Kogler, M., Tortola, L., Novatchkova, M., Bönelt, P., Hoffmann, D., Koglgruber, R., Steffen, U., Schett, G., Busslinger, M., Bergthaler, A., Klein, C., Penninger, JM. |
| 2020 |
Fibroblasts as a source of self-antigens for central immune tolerance.
|
Nat Immunol |
Nitta, T., Tsutsumi, M., Nitta, S., Muro, R., Suzuki, EC., Nakano, K., Tomofuji, Y., Sawa, S., Okamura, T., Penninger, JM., Takayanagi, H. |
| 2020 |
The Role of Angiotensin Converting Enzyme 2 (ACE2) in Modulating Gut Microbiota, Intestinal Inflammation, and Coronavirus Infection.
|
Gastroenterology |
Penninger, JM., Grant, MB., Sung, JJY. |
| 2020 |
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.
|
Cell |
Monteil, V., Kwon, H., Prado, P., Hagelkrüys, A., Wimmer, RA., Stahl, M., Leopoldi, A., Garreta, E., Hurtado Del Pozo, C., Prosper, F., Romero, JP., Wirnsberger, G., Zhang, H., Slutsky, AS., Conder, R., Montserrat, N., Mirazimi, A., Penninger, JM. |
| 2020 |
Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1
K/K
Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung for Inflation at Birth.
|
Front Bioeng Biotechnol |
Szoták-Ajtay, K., Szõke, D., Kovács, G., Andréka, J., Brenner, GB., Giricz, Z., Penninger, J., Kahn, ML., Jakus, Z. |
| 2020 |
Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury.
|
FASEB J |
Bravo-Caparrós, I., Ruiz-Cantero, MC., Perazzoli, G., Cronin, SJF., Vela, JM., Hamed, MF., Penninger, JM., Baeyens, JM., Cobos, EJ., Nieto, FR. |
| 2020 |
Salmonella-based platform for efficient delivery of functional binding proteins to the cytosol.
|
Commun Biol |
Chabloz, A., Schaefer, JV., Kozieradzki, I., Cronin, SJF., Strebinger, D., Macaluso, F., Wald, J., Rabbitts, TH., Plückthun, A., Marlovits, TC., Penninger, JM. |
| 2020 |
Sclerostin expression in trabecular bone is downregulated by osteoclasts.
|
Sci Rep |
Koide, M., Yamashita, T., Murakami, K., Uehara, S., Nakamura, K., Nakamura, M., Matsushita, M., Ara, T., Yasuda, H., Penninger, JM., Takahashi, N., Udagawa, N., Kobayashi, Y. |
| 2020 |
B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction.
|
Nat Commun |
Minato, T., Nirasawa, S., Sato, T., Yamaguchi, T., Hoshizaki, M., Inagaki, T., Nakahara, K., Yoshihashi, T., Ozawa, R., Yokota, S., Natsui, M., Koyota, S., Yoshiya, T., Yoshizawa-Kumagaye, K., Motoyama, S., Gotoh, T., Nakaoka, Y., Penninger, JM., Watanabe, H., Imai, Y., Takahashi, S., Kuba, K. |
| 2020 |
Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.
|
Emerg Microbes Infect |
Appelberg, S., Gupta, S., Svensson Akusjärvi, S., Ambikan, AT., Mikaeloff, F., Saccon, E., Végvári, Á., Benfeitas, R., Sperk, M., Ståhlberg, M., Krishnan, S., Singh, K., Penninger, JM., Mirazimi, A., Neogi, U. |
| 2020 |
Identification of ALK in Thinness.
|
Cell |
Orthofer, M., Valsesia, A., Mägi, R., Wang, QP., Kaczanowska, J., Kozieradzki, I., Leopoldi, A., Cikes, D., Zopf, LM., Tretiakov, EO., Demetz, E., Hilbe, R., Boehm, A., Ticevic, M., Nõukas, M., Jais, A., Spirk, K., Clark, T., Amann, S., Lepamets, M., Neumayr, C., Arnold, C., Dou, Z., Kuhn, V., Novatchkova, M., Cronin, SJF., Tietge, UJF., Müller, S., Pospisilik, JA., Nagy, V., Hui, CC., Lazovic, J., Esterbauer, H., Hagelkruys, A., Tancevski, I., Kiefer, FW., Harkany, T., Haubensak, W., Neely, GG., Metspalu, A., Hager, J., Gheldof, N., Penninger, JM. |
| 2020 |
Targeting the RANKL/RANK/OPG Axis for Cancer Therapy.
|
Front Oncol |
Ming, J., Cronin, SJF., Penninger, JM. |
| 2020 |
HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases.
|
Cancer Res |
Kogler, M., Tortola, L., Negri, GL., Leopoldi, A., El-Naggar, AM., Mereiter, S., Gomez Diaz, C., Nitsch, R., Tortora, D., Kavirayani, AM., Gapp, BV., Rao, S., Uribesalgo, I., Hoffmann, D., Cikes, D., Novatchkova, M., Williams, DA., Trent, JM., Ikeda, F., Daugaard, M., Hagelkruys, A., Sorensen, PH., Penninger, JM. |
| 2020 |
Correction: The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes.
|
PLoS Genet |
Andergassen, D., Muckenhuber, M., Bammer, PC., Kulinski, TM., Theussl, HC., Shimizu, T., Penninger, JM., Pauler, FM., Hudson, QJ. |
| 2020 |
RANKL and OPG and their influence on breast volume changes during pregnancy in healthy women.
|
Sci Rep |
Wunderle, M., Ruebner, M., Häberle, L., Schwenke, E., Hack, CC., Bayer, CM., Koch, MC., Schwitulla, J., Schulz-Wendtland, R., Kozieradzki, I., Lux, MP., Beckmann, MW., Jud, SM., Penninger, JM., Schneider, MO., Fasching, PA. |
| 2020 |
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.
|
Sci Adv |
Stebbing, J., Sánchez Nievas, G., Falcone, M., Youhanna, S., Richardson, P., Ottaviani, S., Shen, JX., Sommerauer, C., Tiseo, G., Ghiadoni, L., Virdis, A., Monzani, F., Rizos, LR., Forfori, F., Avendaño-Céspedes, A., De Marco, S., Carrozzi, L., Lena, F., Sánchez-Jurado, PM., Lacerenza, LG., Cesira, N., Caldevilla-Bernardo, D., Perrella, A., Niccoli, L., Méndez, LS., Matarrese, D., Goletti, D., Tan, YJ., Monteil, V., Dranitsaris, G., Cantini, F., Farcomeni, A., Dutta, S., Burley, SK., Zhang, H., Pistello, M., Li, W., Mas Romero, M., Andrés Pretel, F., Simón-Talero, RS., García-Molina, R., Kutter, C., Felce, JH., Nizami, ZF., Miklosi, AG., Penninger, JM., Menichetti, F., Mirazimi, A., Abizanda, P., Lauschke, VM. |
| 2020 |
Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2.
|
Biochem Biophys Res Commun |
Inoue, M., Hada, K., Shiraishi, H., Yatsuka, H., Fujinami, H., Morisaki, I., Nishida, Y., Matsubara, E., Ishitani, T., Hanada, R., Matsumoto, M., Penninger, JM., Ihara, K., Hanada, T. |
| 2020 |
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.
|
Intensive Care Med |
Zhang, H., Penninger, JM., Li, Y., Zhong, N., Slutsky, AS. |
| 2020 |
Human recombinant soluble ACE2 in severe COVID-19.
|
Lancet Respir Med |
Zoufaly, A., Poglitsch, M., Aberle, JH., Hoepler, W., Seitz, T., Traugott, M., Grieb, A., Pawelka, E., Laferl, H., Wenisch, C., Neuhold, S., Haider, D., Stiasny, K., Bergthaler, A., Puchhammer-Stoeckl, E., Mirazimi, A., Montserrat, N., Zhang, H., Slutsky, AS., Penninger, JM. |
| 2020 |
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.
|
Cell Death Dis |
Li, T., Li, K., Zhang, S., Wang, Y., Xu, Y., Cronin, SJF., Sun, Y., Zhang, Y., Xie, C., Rodriguez, J., Zhou, K., Hagberg, H., Mallard, C., Wang, X., Penninger, JM., Kroemer, G., Blomgren, K., Zhu, C. |
