Publications

Search Publications

Year	Title	Journal	Authors
2017	A Protocol for Multiple Gene Knockout in Mouse Small Intestinal Organoids Using a CRISPR-concatemer.	J Vis Exp	Merenda, A., Andersson-Rolf, A., Mustata, RC., Li, T., Kim, H., Koo, BK.
2017	One-step generation of conditional and reversible gene knockouts.	Nat Methods	Andersson-Rolf, A., Mustata, RC., Merenda, A., Kim, J., Perera, S., Grego, T., Andrews, K., Tremble, K., Silva, JC., Fink, J., Skarnes, WC., Koo, BK.
2017	Adult gastric stem cells and their niches.	Wiley Interdiscip Rev Dev Biol	Bartfeld, S., Koo, BK.
2017	Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium.	Nat Cell Biol	Turco, MY., Gardner, L., Hughes, J., Cindrova-Davies, T., Gomez, MJ., Farrell, L., Hollinshead, M., Marsh, SGE., Brosens, JJ., Critchley, HO., Simons, BD., Hemberger, M., Koo, BK., Moffett, A., Burton, GJ.
2017	DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.	Gastroenterology	Howell, KJ., Kraiczy, J., Nayak, KM., Gasparetto, M., Ross, A., Lee, C., Mak, TN., Koo, BK., Kumar, N., Lawley, T., Sinha, A., Rosenstiel, P., Heuschkel, R., Stegle, O., Zilbauer, M.
2017	Stem Cells in Repair of Gastrointestinal Epithelia.	Physiology (Bethesda)	Andersson-Rolf, A., Zilbauer, M., Koo, BK., Clevers, H.
2016	Rapid, one-step generation of biallelic conditional gene knockouts.	BioRxiv	Andersson-Rolf A, Mustata RC, Merenda A, Perera S, Grego T, Kim J, Andrews K, Fink J, Skarnes WC, Koo BK.
2016	Simultaneous paralogue knockout using a CRISPR-concatemer in mouse small intestinal organoids.	Dev Biol	Andersson-Rolf, A., Merenda, A., Mustata, RC., Li, T., Dietmann, S., Koo, BK.
2016	Organoids: A new in vitro model system for biomedical science and disease modelling and promising source for cell-based transplantation.	Dev Biol	Koo, BK., Huch, M.
2016	Clonal Evolution of Stem Cells in the Gastrointestinal Tract.	Adv Exp Med Biol	Fink, J., Koo, BK.
2016	Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation.	Nat Protoc	Broutier, L., Andersson-Rolf, A., Hindley, CJ., Boj, SF., Clevers, H., Koo, BK., Huch, M.
2015	Stem cell-derived organoid cultures and genome editing tools.	Cell Gene Therapy Insights	Andersson-Rolf A, Koo BK
2015	Adult stem cell lineage tracing and deep tissue imaging.	BMB Rep	Fink, J., Andersson-Rolf, A., Koo, BK.
2015	Modeling mouse and human development using organoid cultures.	Development	Huch, M., Koo, BK.
2015	Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.	Proc Natl Acad Sci U S A	Koo, BK., van Es, JH., van den Born, M., Clevers, H.
2015	Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.	Cell Stem Cell	Schuijers, J., Junker, JP., Mokry, M., Hatzis, P., Koo, BK., Sasselli, V., van der Flier, LG., Cuppen, E., van Oudenaarden, A., Clevers, H.
2014	A video protocol of retroviral infection in primary intestinal organoid culture.	J Vis Exp	Andersson-Rolf, A., Fink, J., Mustata, RC., Koo, BK.
2014	Stem cells marked by the R-spondin receptor LGR5.	Gastroenterology	Koo, BK., Clevers, H.
2013	Retroviral gene expression control in primary organoid cultures.	Curr Protoc Stem Cell Biol	Koo, BK., Sasselli, V., Clevers, H.
2013	Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.	Cell Stem Cell	Schwank, G., Koo, BK., Sasselli, V., Dekkers, JF., Heo, I., Demircan, T., Sasaki, N., Boymans, S., Cuppen, E., van der Ent, CK., Nieuwenhuis, EE., Beekman, JM., Clevers, H.