| 2020 |
Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration.
|
Cell Stem Cell |
Choi, J., Park, JE., Tsagkogeorga, G., Yanagita, M., Koo, BK., Han, N., Lee, JH. |
| 2020 |
Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine.
|
Cell Death Differ |
Seidlitz, T., Koo, BK., Stange, DE. |
| 2020 |
RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
|
EMBO J |
Spit, M., Fenderico, N., Jordens, I., Radaszkiewicz, T., Lindeboom, RG., Bugter, JM., Cristobal, A., Ootes, L., van Osch, M., Janssen, E., Boonekamp, KE., Hanakova, K., Potesil, D., Zdrahal, Z., Boj, SF., Medema, JP., Bryja, V., Koo, BK., Vermeulen, M., Maurice, MM. |
| 2020 |
Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss.
|
Sci Rep |
Morkmued, S., Clauss, F., Schuhbaur, B., Fraulob, V., Mathieu, E., Hemmerlé, J., Clevers, H., Koo, BK., Dollé, P., Bloch-Zupan, A., Niederreither, K. |
| 2020 |
A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.
|
Nat Commun |
Tsukiyama, T., Zou, J., Kim, J., Ogamino, S., Shino, Y., Masuda, T., Merenda, A., Matsumoto, M., Fujioka, Y., Hirose, T., Terai, S., Takahashi, H., Ishitani, T., Nakayama, KI., Ohba, Y., Koo, BK., Hatakeyama, S. |
| 2020 |
Human organoids: model systems for human biology and medicine.
|
Nat Rev Mol Cell Biol |
Kim, J., Koo, BK., Knoblich, JA. |
| 2020 |
Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses.
|
mBio |
Hosmillo, M., Chaudhry, Y., Nayak, K., Sorgeloos, F., Koo, BK., Merenda, A., Lillestol, R., Drumright, L., Zilbauer, M., Goodfellow, I. |
| 2020 |
Human Microphysiological Models of Intestinal Tissue and Gut Microbiome.
|
Front Bioeng Biotechnol |
Steinway, SN., Saleh, J., Koo, BK., Delacour, D., Kim, DH. |
| 2019 |
Human gastric cancer modelling using organoids.
|
Gut |
Seidlitz, T., Merker, SR., Rothe, A., Zakrzewski, F., von Neubeck, C., Grützmann, K., Sommer, U., Schweitzer, C., Schölch, S., Uhlemann, H., Gaebler, AM., Werner, K., Krause, M., Baretton, GB., Welsch, T., Koo, BK., Aust, DE., Klink, B., Weitz, J., Stange, DE. |
| 2019 |
Modeling Host-Virus Interactions in Viral Infectious Diseases Using Stem-Cell-Derived Systems and CRISPR/Cas9 Technology.
|
Viruses |
Kim, J., Koo, BK., Yoon, KJ. |
| 2019 |
Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.
|
Cell Stem Cell |
Han, S., Fink, J., Jörg, DJ., Lee, E., Yum, MK., Chatzeli, L., Merker, SR., Josserand, M., Trendafilova, T., Andersson-Rolf, A., Dabrowska, C., Kim, H., Naumann, R., Lee, JH., Sasaki, N., Mort, RL., Basak, O., Clevers, H., Stange, DE., Philpott, A., Kim, JK., Simons, BD., Koo, BK. |
| 2019 |
A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis.
|
Genes Dev |
Basham, KJ., Rodriguez, S., Turcu, AF., Lerario, AM., Logan, CY., Rysztak, MR., Gomez-Sanchez, CE., Breault, DT., Koo, BK., Clevers, H., Nusse, R., Val, P., Hammer, GD. |
| 2019 |
Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging.
|
Mol Cells |
Wu, SS., Lee, JH., Koo, BK. |
| 2019 |
DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development.
|
Gut |
Kraiczy, J., Nayak, KM., Howell, KJ., Ross, A., Forbester, J., Salvestrini, C., Mustata, R., Perkins, S., Andersson-Rolf, A., Leenen, E., Liebert, A., Vallier, L., Rosenstiel, PC., Stegle, O., Dougan, G., Heuschkel, R., Koo, BK., Zilbauer, M. |
| 2019 |
Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations.
|
Gastroenterology |
Seidlitz, T., Chen, YT., Uhlemann, H., Schölch, S., Kochall, S., Merker, SR., Klimova, A., Hennig, A., Schweitzer, C., Pape, K., Baretton, GB., Welsch, T., Aust, DE., Weitz, J., Koo, BK., Stange, DE. |
| 2018 |
Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer.
|
Open Biol |
Spit, M., Koo, BK., Maurice, MM. |
| 2018 |
DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.
|
Gastroenterology |
Howell, KJ., Kraiczy, J., Nayak, KM., Gasparetto, M., Ross, A., Lee, C., Mak, TN., Koo, BK., Kumar, N., Lawley, T., Sinha, A., Rosenstiel, P., Heuschkel, R., Stegle, O., Zilbauer, M. |
| 2018 |
Morphological alterations of cultured human colorectal matched tumour and healthy organoids.
|
Oncotarget |
Kashfi, SMH., Almozyan, S., Jinks, N., Koo, BK., Nateri, AS. |
| 2018 |
Generation of FLIP and FLIP-FlpE Targeting Vectors for Biallelic Conditional and Reversible Gene Knockouts in Mouse and Human Cells.
|
Methods Mol Biol |
Koo, BK. |
| 2018 |
Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.
|
Cell |
Nanki, K., Toshimitsu, K., Takano, A., Fujii, M., Shimokawa, M., Ohta, Y., Matano, M., Seino, T., Nishikori, S., Ishikawa, K., Kawasaki, K., Togasaki, K., Takahashi, S., Sukawa, Y., Ishida, H., Sugimoto, S., Kawakubo, H., Kim, J., Kitagawa, Y., Sekine, S., Koo, BK., Kanai, T., Sato, T. |
