| 2017 |
A Protocol for Multiple Gene Knockout in Mouse Small Intestinal Organoids Using a CRISPR-concatemer.
|
J Vis Exp |
Merenda, A., Andersson-Rolf, A., Mustata, RC., Li, T., Kim, H., Koo, BK. |
| 2017 |
One-step generation of conditional and reversible gene knockouts.
|
Nat Methods |
Andersson-Rolf, A., Mustata, RC., Merenda, A., Kim, J., Perera, S., Grego, T., Andrews, K., Tremble, K., Silva, JC., Fink, J., Skarnes, WC., Koo, BK. |
| 2017 |
Adult gastric stem cells and their niches.
|
Wiley Interdiscip Rev Dev Biol |
Bartfeld, S., Koo, BK. |
| 2017 |
Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium.
|
Nat Cell Biol |
Turco, MY., Gardner, L., Hughes, J., Cindrova-Davies, T., Gomez, MJ., Farrell, L., Hollinshead, M., Marsh, SGE., Brosens, JJ., Critchley, HO., Simons, BD., Hemberger, M., Koo, BK., Moffett, A., Burton, GJ. |
| 2017 |
Stem Cells in Repair of Gastrointestinal Epithelia.
|
Physiology (Bethesda) |
Andersson-Rolf, A., Zilbauer, M., Koo, BK., Clevers, H. |
| 2016 |
Rapid, one-step generation of biallelic conditional gene knockouts.
|
BioRxiv |
Andersson-Rolf A, Mustata RC, Merenda A, Perera S, Grego T, Kim J, Andrews K, Fink J, Skarnes WC, Koo BK. |
| 2016 |
Simultaneous paralogue knockout using a CRISPR-concatemer in mouse small intestinal organoids.
|
Dev Biol |
Andersson-Rolf, A., Merenda, A., Mustata, RC., Li, T., Dietmann, S., Koo, BK. |
| 2016 |
Organoids: A new in vitro model system for biomedical science and disease modelling and promising source for cell-based transplantation.
|
Dev Biol |
Koo, BK., Huch, M. |
| 2016 |
Clonal Evolution of Stem Cells in the Gastrointestinal Tract.
|
Adv Exp Med Biol |
Fink, J., Koo, BK. |
| 2016 |
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation.
|
Nat Protoc |
Broutier, L., Andersson-Rolf, A., Hindley, CJ., Boj, SF., Clevers, H., Koo, BK., Huch, M. |
| 2015 |
Stem cell-derived organoid cultures and genome editing tools.
|
Cell Gene Therapy Insights |
Andersson-Rolf A, Koo BK |
| 2015 |
Adult stem cell lineage tracing and deep tissue imaging.
|
BMB Rep |
Fink, J., Andersson-Rolf, A., Koo, BK. |
| 2015 |
Modeling mouse and human development using organoid cultures.
|
Development |
Huch, M., Koo, BK. |
| 2015 |
Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.
|
Proc Natl Acad Sci U S A |
Koo, BK., van Es, JH., van den Born, M., Clevers, H. |
| 2015 |
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.
|
Cell Stem Cell |
Schuijers, J., Junker, JP., Mokry, M., Hatzis, P., Koo, BK., Sasselli, V., van der Flier, LG., Cuppen, E., van Oudenaarden, A., Clevers, H. |
| 2014 |
A video protocol of retroviral infection in primary intestinal organoid culture.
|
J Vis Exp |
Andersson-Rolf, A., Fink, J., Mustata, RC., Koo, BK. |
| 2014 |
Stem cells marked by the R-spondin receptor LGR5.
|
Gastroenterology |
Koo, BK., Clevers, H. |
| 2013 |
Retroviral gene expression control in primary organoid cultures.
|
Curr Protoc Stem Cell Biol |
Koo, BK., Sasselli, V., Clevers, H. |
| 2013 |
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.
|
Cell Stem Cell |
Schwank, G., Koo, BK., Sasselli, V., Dekkers, JF., Heo, I., Demircan, T., Sasaki, N., Boymans, S., Cuppen, E., van der Ent, CK., Nieuwenhuis, EE., Beekman, JM., Clevers, H. |
| 2013 |
Generation of BAC transgenic epithelial organoids.
|
PLoS One |
Schwank, G., Andersson-Rolf, A., Koo, BK., Sasaki, N., Clevers, H. |
