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Year Title Journal Authors
2017 Fused cerebral organoids model interactions between brain regions. Nat Methods Bagley, JA., Reumann, D., Bian, S., Lévi-Strauss, J., Knoblich, JA.
2017 LOX Fails to Substitute for RANKL in Osteoclastogenesis. J Bone Miner Res Tsukasaki, M., Hamada, K., Okamoto, K., Nagashima, K., Terashima, A., Komatsu, N., Win, SJ., Okamura, T., Nitta, T., Yasuda, H., Penninger, JM., Takayanagi, H.
2017 Human tissues in a dish: The research and ethical implications of organoid technology. Science Bredenoord, AL., Clevers, H., Knoblich, JA.
2017 Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline. Psychopharmacology (Berl) Openshaw, RL., Thomson, DM., Penninger, JM., Pratt, JA., Morris, BJ.
2017 Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice. Proc Natl Acad Sci U S A Tejada, MA., Montilla-García, A., Cronin, SJ., Cikes, D., Sánchez-Fernández, C., González-Cano, R., Ruiz-Cantero, MC., Penninger, JM., Vela, JM., Baeyens, JM., Cobos, EJ.
2017 Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding. Neuron Falk, S., Bugeon, S., Ninkovic, J., Pilz, GA., Postiglione, MP., Cremer, H., Knoblich, JA., Götz, M.
2017 Self-organized developmental patterning and differentiation in cerebral organoids. EMBO J Renner, M., Lancaster, MA., Bian, S., Choi, H., Ku, T., Peer, A., Chung, K., Knoblich, JA.
2017 Negative Regulators of an RNAi-Heterochromatin Positive Feedback Loop Safeguard Somatic Genome Integrity in Tetrahymena. Cell Rep Suhren, JH., Noto, T., Kataoka, K., Gao, S., Liu, Y., Mochizuki, K.
2017 The hope and the hype of organoid research. Development Huch, M., Knoblich, JA., Lutolf, MP., Martinez-Arias, A.
2017 ELABELA - APJ axis protects from pressure overload heart failure and Angiotensin II-induced cardiac damage. Cardiovasc Res Sato, T., Sato, C., Kadowaki, A., Watanabe, H., Ho, L., Ishida, J., Yamaguchi, T., Kimura, A., Fukamizu, A., Penninger, JM., Reversade, B., Ito, H., Imai, Y., Kuba, K.
2017 DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell Choi, J., Clement, K., Huebner, AJ., Webster, J., Rose, CM., Brumbaugh, J., Walsh, RM., Lee, S., Savol, A., Etchegaray, JP., Gu, H., Boyle, P., Elling, U., Mostoslavsky, R., Sadreyev, R., Park, PJ., Gygi, SP., Meissner, A., Hochedlinger, K.
2017 RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer. Genes Dev Rao, S., Sigl, V., Wimmer, RA., Novatchkova, M., Jais, A., Wagner, G., Handschuh, S., Uribesalgo, I., Hagelkruys, A., Kozieradzki, I., Tortola, L., Nitsch, R., Cronin, SJ., Orthofer, M., Branstetter, D., Canon, J., Rossi, J., D'Arcangelo, M., Botling, J., Micke, P., Fleur, L., Edlund, K., Bergqvist, M., Ekman, S., Lendl, T., Popper, H., Takayanagi, H., Kenner, L., Hirsch, FR., Dougall, W., Penninger, JM.
2017 Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis. Nat Microbiol Beckham, KS., Ciccarelli, L., Bunduc, CM., Mertens, HD., Ummels, R., Lugmayr, W., Mayr, J., Rettel, M., Savitski, MM., Svergun, DI., Bitter, W., Wilmanns, M., Marlovits, TC., Parret, AH., Houben, EN.
2017 Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition. Nature Flyamer, IM., Gassler, J., Imakaev, M., Brandão, HB., Ulianov, SV., Abdennur, N., Razin, SV., Mirny, LA., Tachibana-Konwalski, K.
2017 Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell Li, Y., Muffat, J., Omer, A., Bosch, I., Lancaster, MA., Sur, M., Gehrke, L., Knoblich, JA., Jaenisch, R.
2017 Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer. Oncotarget Kiechl, S., Schramek, D., Widschwendter, M., Fourkala, EO., Zaikin, A., Jones, A., Jaeger, B., Rack, B., Janni, W., Scholz, C., Willeit, J., Weger, S., Mayr, A., Teschendorff, A., Rosenthal, A., Fraser, L., Philpott, S., Dubeau, L., Keshtgar, M., Roylance, R., Jacobs, IJ., Menon, U., Schett, G., Penninger, JM.
2017 Heterochromatin aggregation during DNA elimination in Tetrahymena is facilitated by a prion-like protein. J Cell Sci Kataoka, K., Mochizuki, K.
2017 Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation. J Immunol Tran, CW., Saibil, SD., Le Bihan, T., Hamilton, SR., Lang, KS., You, H., Lin, AE., Garza, KM., Elford, AR., Tai, K., Parsons, ME., Wigmore, K., Vainberg, MG., Penninger, JM., Woodgett, JR., Mak, TW., Ohashi, PS.
2017 Frontline Science: Coincidental null mutation of Csf2r? in a colony of PI3K?-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection. J Leukoc Biol Schneider, C., Nobs, SP., Heer, AK., Hirsch, E., Penninger, J., Siggs, OM., Kopf, M.
2017 Molecular definitions of autophagy and related processes. EMBO J Galluzzi, L., Baehrecke, EH., Ballabio, A., Boya, P., Bravo-San Pedro, JM., Cecconi, F., Choi, AM., Chu, CT., Codogno, P., Colombo, MI., Cuervo, AM., Debnath, J., Deretic, V., Dikic, I., Eskelinen, EL., Fimia, GM., Fulda, S., Gewirtz, DA., Green, DR., Hansen, M., Harper, JW., Jäättelä, M., Johansen, T., Juhasz, G., Kimmelman, AC., Kraft, C., Ktistakis, NT., Kumar, S., Levine, B., Lopez-Otin, C., Madeo, F., Martens, S., Martinez, J., Melendez, A., Mizushima, N., Münz, C., Murphy, LO., Penninger, JM., Piacentini, M., Reggiori, F., Rubinsztein, DC., Ryan, KM., Santambrogio, L., Scorrano, L., Simon, AK., Simon, HU., Simonsen, A., Tavernarakis, N., Tooze, SA., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q., Kroemer, G.