2021 |
A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.
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J Exp Med |
Hagelkruys, A., Wirnsberger, G., Stadlmann, J., Wöhner, M., Horrer, M., Vilagos, B., Jonsson, G., Kogler, M., Tortola, L., Novatchkova, M., Bönelt, P., Hoffmann, D., Koglgruber, R., Steffen, U., Schett, G., Busslinger, M., Bergthaler, A., Klein, C., Penninger, JM. |
2020 |
Fast and highly efficient affinity enrichment of Azide-A-DSBSO cross-linked peptides.
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J Proteome Res |
Matzinger, M., Kandioller, W., Doppler, P., Heiss, EH., Mechtler, K. |
2020 |
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.
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Sci Adv |
Stebbing, J., Sánchez Nievas, G., Falcone, M., Youhanna, S., Richardson, P., Ottaviani, S., Shen, JX., Sommerauer, C., Tiseo, G., Ghiadoni, L., Virdis, A., Monzani, F., Rizos, LR., Forfori, F., Avendaño-Céspedes, A., De Marco, S., Carrozzi, L., Lena, F., Sánchez-Jurado, PM., Lacerenza, LG., Cesira, N., Caldevilla-Bernardo, D., Perrella, A., Niccoli, L., Méndez, LS., Matarrese, D., Goletti, D., Tan, YJ., Monteil, V., Dranitsaris, G., Cantini, F., Farcomeni, A., Dutta, S., Burley, SK., Zhang, H., Pistello, M., Li, W., Mas Romero, M., Andrés Pretel, F., Simón-Talero, RS., García-Molina, R., Kutter, C., Felce, JH., Nizami, ZF., Miklosi, AG., Penninger, JM., Menichetti, F., Mirazimi, A., Abizanda, P., Lauschke, VM. |
2020 |
Human Microphysiological Models of Intestinal Tissue and Gut Microbiome.
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Front Bioeng Biotechnol |
Steinway, SN., Saleh, J., Koo, BK., Delacour, D., Kim, DH. |
2020 |
Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex
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BioRxiv |
Oliver L. Eichmüller, Nina S. Corsini, Ábel Vértesy, Theresa Scholl, Victoria-Elisabeth Gruber, Angela M. Peer, Julia Chu, Maria Novatchkova, Mercedes F. Paredes, Martha Feucht, Jürgen A. Knoblich |
2020 |
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.
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Intensive Care Med |
Zhang, H., Penninger, JM., Li, Y., Zhong, N., Slutsky, AS. |
2020 |
A joint action in times of pandemic: the German BioImaging recommendations for operating imaging core facilities during the SARS-Cov-2 emergency.
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Cytometry A |
Dietzel, S., Ferrando-May, E., Fried, H., Kukat, C., Naumann, A., Nitschke, R., Pasierbek, P., Peychl, J., Rasse, TM., Schroth-Diez, B., Stöckl, MT., Terjung, S., Thuenauer, R., Tulok, S., Weidtkamp-Peters, S. |
2020 |
Fibroblasts as a source of self-antigens for central immune tolerance.
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Nat Immunol |
Nitta, T., Tsutsumi, M., Nitta, S., Muro, R., Suzuki, EC., Nakano, K., Tomofuji, Y., Sawa, S., Okamura, T., Penninger, JM., Takayanagi, H. |
2020 |
Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1
K/K
Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung for Inflation at Birth.
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Front Bioeng Biotechnol |
Szoták-Ajtay, K., Szõke, D., Kovács, G., Andréka, J., Brenner, GB., Giricz, Z., Penninger, J., Kahn, ML., Jakus, Z. |
2020 |
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.
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Cell Death Dis |
Li, T., Li, K., Zhang, S., Wang, Y., Xu, Y., Cronin, SJF., Sun, Y., Zhang, Y., Xie, C., Rodriguez, J., Zhou, K., Hagberg, H., Mallard, C., Wang, X., Penninger, JM., Kroemer, G., Blomgren, K., Zhu, C. |
2020 |
Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism.
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Elife |
Ahel, J., Lehner, A., Vogel, A., Schleiffer, A., Meinhart, A., Haselbach, D., Clausen, T. |
2020 |
Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells.
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Cell Rep |
Castel, G., Meistermann, D., Bretin, B., Firmin, J., Blin, J., Loubersac, S., Bruneau, A., Chevolleau, S., Kilens, S., Chariau, C., Gaignerie, A., Francheteau, Q., Kagawa, H., Charpentier, E., Flippe, L., François-Campion, V., Haider, S., Dietrich, B., Knöfler, M., Arima, T., Bourdon, J., Rivron, N., Masson, D., Fournier, T., Okae, H., Fréour, T., David, L. |
2020 |
Cardioids reveal self-organizing principles of human cardiogenesis
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BioRxiv |
Pablo Hofbauer, Stefan Jahnel, Nora Papai, Magdalena Giesshammer, Mirjam Penc, Katherina Tavernini, Nastasja Grdseloff, Christy Meledeth, Alison Deyett, Clara Schmidt, Claudia Ctortecka, Šejla Šalic, Maria Novatchkova, Sasha Mendjan |
2020 |
Human organoids: model systems for human biology and medicine.
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Nat Rev Mol Cell Biol |
Kim, J., Koo, BK., Knoblich, JA. |
2020 |
ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity.
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Science |
Pinto, PH., Kroupova, A., Schleiffer, A., Mechtler, K., Jinek, M., Weitzer, S., Martinez, J. |
2020 |
B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction.
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Nat Commun |
Minato, T., Nirasawa, S., Sato, T., Yamaguchi, T., Hoshizaki, M., Inagaki, T., Nakahara, K., Yoshihashi, T., Ozawa, R., Yokota, S., Natsui, M., Koyota, S., Yoshiya, T., Yoshizawa-Kumagaye, K., Motoyama, S., Gotoh, T., Nakaoka, Y., Penninger, JM., Watanabe, H., Imai, Y., Takahashi, S., Kuba, K. |
2020 |
A human tissue screen identifies a regulator of ER secretion as a brain size determinant.
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Science |
Esk, C., Lindenhofer, D., Haendeler, S., Wester, RA., Pflug, F., Schroeder, B., Bagley, JA., Elling, U., Zuber, J., von Haeseler, A., Knoblich, JA. |
2020 |
The emergence of genome architecture and zygotic genome activation.
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Curr Opin Cell Biol |
Vallot, A., Tachibana, K. |
2020 |
CLP1 acts as the main RNA kinase in mice.
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Biochem Biophys Res Commun |
Fujinami, H., Shiraishi, H., Hada, K., Inoue, M., Morisaki, I., Higa, R., Shin, T., Kobayashi, T., Hanada, R., Penninger, JM., Mimata, H., Hanada, T. |
2020 |
Human recombinant soluble ACE2 in severe COVID-19.
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Lancet Respir Med |
Zoufaly, A., Poglitsch, M., Aberle, JH., Hoepler, W., Seitz, T., Traugott, M., Grieb, A., Pawelka, E., Laferl, H., Wenisch, C., Neuhold, S., Haider, D., Stiasny, K., Bergthaler, A., Puchhammer-Stoeckl, E., Mirazimi, A., Montserrat, N., Zhang, H., Slutsky, AS., Penninger, JM. |