Not just housekeeping: A new way to control protein production in stem cells.
Image depicts a E4.5 mouse blastocyst showing high levels of protein synthesis (green) and HTATSF1 expression (red). (c)IMBA
Why tumor stem cells stay "forever young": Asymmetric localization of the lncRNA cherub in dividing neuroblasts (neural stem cells). cherub localizes to the basal cell pole.
cherub (red), apical cell marker (white), DNA (cyan). (c)IMBA
ASSCR founding committee: Johann Bauer, Georg Dechant, Frank Edenhofer, Elly Tanaka, Markus Hengstschläger, Dirk Strunk, Peter Valent, Jürgen Knoblich, Katharina Günther (c)IMBA
UniStem Day 2018: Jürgen Knoblich (IMBA), Karin Garber (Vienna Open Lab), Madalina Mirea (IMBA) und Chukwuma Agu (IMBA) mit den interessierten SchülerInnen beim UniStem Day 2018. (c)IMBA
Taking screening methods to the next level: CRISPR-UMI relies on the addition of a high complexity barcoding system – or Unique Molecular Identifier (UMI) – that uniquely marks each mutant clone within a population, thus it allows tracking single mutants within a population of cells.
HAPLOBANK - a biobank of reversible mutant embryonic stem cells: Haplobank contains over 100,000 mutated, conditional mouse embryonic stem cell lines, targeting about 70% of the protein-coding genome.
IMBA group leader Stefan Ameres and Lexogen CEO Alexander Seitz
IMBA Group leader Stefan Ameres and Lexogen CEO ALexander Seitz
Glycosylation: Mapping uncharted territory: SugarQb is a platform that enables global insights into protein glycosylation and glycan modifications in biological systems. (c)IMBA
Ricin only lethal in combination with sugar: Jasmin Taubenschmid, first author of the study
How cells hack their own genes: Image of a developing drosophila ovary with DNA stained in blue. Using staining for specific proteins researchers could locate the gene hacking events to the white foci in the germline nuclei. (c)IMBA
Sabrina Ladstätter wins ÖAW best pager award. Image: Sabrina Ladstätter, OeAW best paper awardee
IMBA Research Report 2015 (5,7 MB; download as pdf)
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Josef Penninger, Scientific Director (c)IMBA/Michael Sazel
Jürgen Knoblich, Deputy Scientific Director (c)IMBA/Michael Sazel
Michael Krebs, Administrative Director (c)IMBA/Michael Sazel