(2013)
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Harzer, H., Berger, C., Conder, R., Schmauss, G., Knoblich, JA. (2013). FACS purification of Drosophila larval neuroblasts for next-generation sequencing.
Nat Protoc. 8(6):1088-99
(abstract)
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Sparmann, A., Xie, Y., Verhoeven, E., Vermeulen, M., Lancini, C., Gargiulo, G., Hulsman, D., Mann, M., Knoblich, JA., van Lohuizen, M. (2013). The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.
EMBO J.
(abstract)
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(2012)
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Berger, C., Harzer, H., Burkard, TR., Steinmann, J., van der Horst, S., Laurenson, AS., Novatchkova, M., Reichert, H., Knoblich, JA. (2012). FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal.
Cell Rep. 2(2):407-18
(abstract)
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Goulas, S., Conder, R., Knoblich, JA. (2012). The par complex and integrins direct asymmetric cell division in adult intestinal stem cells.
Cell Stem Cell. 11(4):529-40
(abstract)
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Homem, CC., Knoblich, JA. (2012). Drosophila neuroblasts: a model for stem cell biology.
Development. 139(23):4297-310
(abstract)
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Lancaster, MA., Knoblich, JA. (2012). Spindle orientation in mammalian cerebral cortical development.
Curr Opin Neurobiol. 22(5):737-46
(abstract)
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(2011)
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Khazaei, MR., Bunk, EC., Hillje, AL., Jahn, HM., Riegler, EM., Knoblich, JA., Young, P., Schwamborn, JC. (2011). The E3-ubiquitin ligase TRIM2 regulates neuronal polarization.
J Neurochem. 117(1):29-37
(abstract)
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Neumüller, RA., Richter, C., Fischer, A., Novatchkova, M., Neumüller, KG., Knoblich, JA. (2011). Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.
Cell Stem Cell. 8(5):580-93
(abstract)
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Postiglione, MP., Jüschke, C., Xie, Y., Haas, GA., Charalambous, C., Knoblich, JA. (2011). Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex.
Neuron. 72(2):269-84
(abstract)
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Richter, C., Oktaba, K., Steinmann, J., Müller, J., Knoblich, JA. (2011). The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements.
Nat Cell Biol. 13(9):1029-39
(abstract)
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(2010)
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Knoblich, JA. (2010). Asymmetric cell division: recent developments and their implications for tumour biology.
Nat Rev Mol Cell Biol. 11(12):849-60
(abstract)
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(2009)
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Conder, R., Knoblich, JA. (2009). Fly stem cell research gets infectious.
Cell. 137(7):1185-7
(abstract)
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Coumailleau, F., Fürthauer, M., Knoblich, JA., González-Gaitán, M. (2009). Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division.
Nature. 458(7241):1051-5
(abstract)
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Mummery-Widmer, JL., Yamazaki, M., Stoeger, T., Novatchkova, M., Bhalerao, S., Chen, D., Dietzl, G., Dickson, BJ., Knoblich, JA. (2009). Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi.
Nature. 458(7241):987-92
(abstract)
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Neumüller, RA., Knoblich, JA. (2009). Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer.
Genes Dev. 23(23):2675-99
(abstract)
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Neumüller, RA., Knoblich, JA. (2009). Wicked views on stem cell news.
Nat Cell Biol. 11(6):678-9
(abstract)
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Schwamborn, JC., Berezikov, E., Knoblich, JA. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.
Cell. 136(5):913-25
(abstract)
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(2008)
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Barral, Y., Knoblich, J. (2008). Cell division, growth and death.
Curr Opin Cell Biol. 20(6):647-9
(abstract)
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Benetka, W., Mehlmer, N., Maurer-Stroh, S., Sammer, M., Koranda, M., Neumüller, R., Betschinger, J., Knoblich, JA., Teige, M., Eisenhaber, F. (2008). Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling.
Cell Cycle. 7(23):3709-19
(abstract)
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Bowman, SK., Rolland, V., Betschinger, J., Kinsey, KA., Emery, G., Knoblich, JA. (2008). The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila.
Dev Cell. 14(4):535-46
(abstract)
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Jüschke, C., Knoblich, JA. (2008). Purification of Drosophila protein complexes for mass spectrometry.
Methods Mol Biol. 420:347-58
(abstract)
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Knoblich, JA. (2008). Mechanisms of asymmetric stem cell division.
Cell. 132(4):583-97
(abstract)
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Neumüller, RA., Betschinger, J., Fischer, A., Bushati, N., Poernbacher, I., Mechtler, K., Cohen, SM., Knoblich, JA. (2008). Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.
Nature. 454(7201):241-5
(abstract)
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Schwamborn, JC., Knoblich, JA. (2008). LIS1 and spindle orientation in neuroepithelial cells.
Cell Stem Cell. 2(3):193-4
(abstract)
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Speicher, S., Fischer, A., Knoblich, J., Carmena, A. (2008). The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors.
Curr Biol. 18(11):831-7
(abstract)
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Wirtz-Peitz, F., Nishimura, T., Knoblich, JA. (2008). Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization.
Cell. 135(1):161-73
(abstract)
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(2007)
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Knoblich, J. (2007). On the backroads to cellular asymmetry.
Development (Cambridge, England). 134(24):4311-3
(abstract)
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(2006)
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Betschinger, J., Mechtler, K., Knoblich, JA. (2006). Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.
Cell. 124(6):1241-53
(abstract)
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Bowman, SK., Neumüller, RA., Novatchkova, M., Du, Q., Knoblich, JA. (2006). The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division.
Dev Cell. 10(6):731-42
(abstract)
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Emery, G., Knoblich, JA. (2006). Endosome dynamics during development.
Curr Opin Cell Biol. 18(4):407-15
(abstract)
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Gallagher, CM., Knoblich, JA. (2006). The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila.
Dev Cell. 11(5):641-53
(abstract)
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Hutterer, A., Berdnik, D., Wirtz-Peitz, F., Zigman, M., Schleiffer, A., Knoblich, JA. (2006). Mitotic activation of the kinase Aurora-A requires its binding partner Bora.
Dev Cell. 11(2):147-57
(abstract)
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Knoblich, JA. (2006). Cell biology. Sara splits the signal.
Science. 314(5802):1094-6
(abstract)
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Vishnu, S., Hertenstein, A., Betschinger, J., Knoblich, JA., Gert de Couet, H., Fischbach, KF. (2006). The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila.
Dev Biol. 289(2):296-307
(abstract)
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Wirtz-Peitz, F., Knoblich, JA. (2006). Lethal giant larvae take on a life of their own.
Trends Cell Biol. 16(5):234-41
(abstract)
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(2005)
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Betschinger, J., Eisenhaber, F., Knoblich, JA. (2005). Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.
Curr Biol. 15(3):276-82
(abstract)
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Bhalerao, S., Berdnik, D., Török, T., Knoblich, JA. (2005). Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila.
Curr Biol. 15(17):1583-90
(abstract)
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Emery, G., Hutterer, A., Berdnik, D., Mayer, B., Wirtz-Peitz, F., Gaitan, MG., Knoblich, JA. (2005). Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system.
Cell. 122(5):763-73
(abstract)
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Hampoelz, B., Hoeller, O., Bowman, SK., Dunican, D., Knoblich, JA. (2005). Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins.
Nat Cell Biol. 7(11):1099-105
(abstract)
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Hutterer, A., Knoblich, JA. (2005). Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs.
EMBO Rep. 6(9):836-42
(abstract)
|
Jafar-Nejad, H., Andrews, HK., Acar, M., Bayat, V., Wirtz-Peitz, F., Mehta, SQ., Knoblich, JA., Bellen, HJ. (2005). Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.
Dev Cell. 9(3):351-63
(abstract)
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Knoblich, JA. (2005). Pins for spines.
Nat Cell Biol. 7(12):1157-8
(abstract)
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Knoblich, JA. (2005). Neurobiology: getting axons going.
Nature. 436(7051):632-3
(abstract)
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Mayer, B., Emery, G., Berdnik, D., Wirtz-Peitz, F., Knoblich, JA. (2005). Quantitative analysis of protein dynamics during asymmetric cell division.
Curr Biol. 15(20):1847-54
(abstract)
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Zarnescu, DC., Jin, P., Betschinger, J., Nakamoto, M., Wang, Y., Dockendorff, TC., Feng, Y., Jongens, TA., Sisson, JC., Knoblich, JA., Warren, ST., Moses, K. (2005). Fragile X protein functions with lgl and the par complex in flies and mice.
Dev Cell. 8(1):43-52
(abstract)
|
Zigman, M., Cayouette, M., Charalambous, C., Schleiffer, A., Hoeller, O., Dunican, D., McCudden, CR., Firnberg, N., Barres, BA., Siderovski, DP., Knoblich, JA. (2005). Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina.
Neuron. 48(4):539-45
(abstract)
|
(2004)
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Betschinger, J., Knoblich, JA. (2004). Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates.
Curr Biol. 14(16):R674-85
(abstract)
|
Hampoelz, B., Knoblich, JA. (2004). Heterotrimeric G proteins: new tricks for an old dog.
Cell. 119(4):453-6
(abstract)
|
Hutterer, A., Betschinger, J., Petronczki, M., Knoblich, JA. (2004). Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis.
Dev Cell. 6(6):845-54
(abstract)
|
(2003)
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Betschinger, J., Mechtler, K., Knoblich, JA. (2003). The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.
Nature. 422(6929):326-30
(abstract)
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Blumer, JB., Bernard, ML., Peterson, YK., Nezu, J., Chung, P., Dunican, DJ., Knoblich, JA., Lanier, SM. (2003). Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha.
J Biol Chem. 278(26):23217-20
(abstract)
|
Subramanian, A., Prokop, A., Yamamoto, M., Sugimura, K., Uemura, T., Betschinger, J., Knoblich, JA., Volk, T. (2003). Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction.
Curr Biol. 13(13):1086-95
(abstract)
|
(2002)
|
Berdnik, D., Knoblich, JA. (2002). Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis.
Curr Biol. 12(8):640-7
(abstract)
|
Berdnik, D., Török, T., González-Gaitán, M., Knoblich, JA. (2002). The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila.
Dev Cell. 3(2):221-31
(abstract)
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Tekotte, H., Berdnik, D., Török, T., Buszczak, M., Jones, LM., Cooley, L., Knoblich, JA., Davis, I. (2002). Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila.
Dev Biol. 244(2):396-406
(abstract)
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(2001)
|
Bulgheresi, S., Kleiner, E., Knoblich, JA. (2001). Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell division.
J Cell Sci. 114(Pt 20):3655-62
(abstract)
|
Huynh, JR., Petronczki, M., Knoblich, JA., St Johnston, D. (2001). Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila.
Curr Biol. 11(11):901-6
(abstract)
|
Knoblich, JA. (2001). Asymmetric cell division during animal development.
Nat Rev Mol Cell Biol. 2(1):11-20
(abstract)
|
Knoblich, JA. (2001). The Drosophila nervous system as a model for asymmetric cell division.
Symp Soc Exp Biol. (53):75-89
(abstract)
|
Petronczki, M., Knoblich, JA. (2001). DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila.
Nat Cell Biol. 3(1):43-9
(abstract)
|
Schaefer, M., Knoblich, JA. (2001). Protein localization during asymmetric cell division.
Exp Cell Res. 271(1):66-74
(abstract)
|
Schaefer, M., Petronczki, M., Dorner, D., Forte, M., Knoblich, JA. (2001). Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system.
Cell. 107(2):183-94
(abstract)
|
(2000)
|
Knoblich, JA. (2000). Epithelial polarity: the ins and outs of the fly epidermis.
Curr Biol. 10(21):R791-4
(abstract)
|
Schaefer, M., Shevchenko, A., Shevchenko, A., Knoblich, JA. (2000). A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila.
Curr Biol. 10(7):353-62
(abstract)
|
(1999)
|
Knoblich, JA., Jan, LY., Jan, YN. (1999). Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization.
Curr Biol. 9(3):155-8
(abstract)
|
Schober, M., Schaefer, M., Knoblich, JA. (1999). Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.
Nature. 402(6761):548-51
(abstract)
|
(1998)
|
Glotzer, M., Knoblich, JA. (1998). Cell multiplication - editorial overview.
Current Opinion in Cell Biology . 10:739-41
|
Jacobs, HW., Knoblich, JA., Lehner, CF. (1998). Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B.
Genes Dev. 12(23):3741-51
(abstract)
|
Shen, CP., Knoblich, JA., Chan, YM., Jiang, MM., Jan, LY., Jan, YN. (1998). Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila.
Genes Dev. 12(12):1837-46
(abstract)
|
(1997)
|
Knoblich, JA. (1997). Mechanisms of asymmetric cell division during animal development.
Curr Opin Cell Biol. 9(6):833-41
(abstract)
|
Knoblich, JA., Jan, LY., Jan, YN. (1997). Asymmetric segregation of the Drosophila numb protein during mitosis: facts and speculations.
Cold Spring Harb Symp Quant Biol. 62:71-7
(abstract)
|
Knoblich, JA., Jan, LY., Jan, YN. (1997). The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization.
Proc Natl Acad Sci U S A. 94(24):13005-10
(abstract)
|
(1996)
|
Frise, E., Knoblich, JA., Younger-Shepherd, S., Jan, LY., Jan, YN. (1996). The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage.
Proc Natl Acad Sci U S A. 93(21):11925-32
(abstract)
|
Kraut, R., Chia, W., Jan, LY., Jan, YN., Knoblich, JA. (1996). Role of inscuteable in orienting asymmetric cell divisions in Drosophila.
Nature. 383(6595):50-5
(abstract)
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(1995)
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Knoblich, JA., Jan, LY., Jan, YN. (1995). Asymmetric segregation of Numb and Prospero during cell division.
Nature. 377(6550):624-7
(abstract)
|
Kreutzer, MA., Richards, JP., De Silva-Udawatta, MN., Temenak, JJ., Knoblich, JA., Lehner, CF., Bennett, KL. (1995). Caenorhabditis elegans cyclin A- and B-type genes: a cyclin A multigene family, an ancestral cyclin B3 and differential germline expression.
J Cell Sci. 108 ( Pt 6):2415-24
(abstract)
|
Rhyu, MS., Knoblich, JA. (1995). Spindle orientation and asymmetric cell fate.
Cell. 82(4):523-6
(abstract)
|
Sauer, K., Knoblich, JA., Richardson, H., Lehner, CF. (1995). Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis.
Genes Dev. 9(11):1327-39
(abstract)
|
(1994)
|
Knoblich, JA., Sauer, K., Jones, L., Richardson, H., Saint, R., Lehner, CF. (1994). Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.
Cell. 77(1):107-20
(abstract)
|
(1993)
|
Knoblich, JA., Lehner, CF. (1993). Synergistic action of Drosophila cyclins A and B during the G2-M transition.
EMBO J. 12(1):65-74
(abstract)
|
(1992)
|
Lehner, CF., Ried, G., Stern, B., Knoblich, JA. (1992). Cyclins and cdc2 kinases in Drosophila: genetic analyses in a higher eukaryote.
Ciba Found Symp. 170:97-109; discussion 110-4
(abstract)
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