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Publications

(2012)
 
Popow, J., Schleiffer, A., Martinez, J. (2012). Diversity and roles of (t)RNA ligases. Cell Mol Life Sci. (abstract)
 
(2011)
 
Popow, J., Englert, M., Weitzer, S., Schleiffer, A., Mierzwa, B., Mechtler, K., Trowitzsch, S., Will, CL., Lührmann, R., Söll, D., Martinez, J. (2011). HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science. 331(6018):760-4 (abstract)
 
(2010)
 
Braglia, P., Heindl, K., Schleiffer, A., Martinez, J., Proudfoot, NJ. (2010). Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I. EMBO Rep. 11(10):758-64 (abstract)
 
Heindl, K., Martinez, J. (2010). Nol9 is a novel polynucleotide 5'-kinase involved in ribosomal RNA processing. EMBO J. 29(24):4161-71 (abstract)
 
(2009)
 
Gebeshuber, CA., Zatloukal, K., Martinez, J. (2009). miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. EMBO Rep. 10(4):400-5 (abstract)
 
Karayel, E., Bürckstümmer, T., Bilban, M., Dürnberger, G., Weitzer, S., Martinez, J., Superti-Furga, G. (2009). The TLR-independent DNA recognition pathway in murine macrophages: Ligand features and molecular signature. Eur J Immunol. 39(7):1929-36 (abstract)
 
Nielsen, AF., Gloggnitzer, J., Martinez, J. (2009). Ars2 and the Cap-Binding Complex Team up for Silencing. Cell. 138(2):224-6 (abstract)
 
Nielsen, AF., Gloggnitzer, J., Martinez, J. (2009). MicroRNAs cross the line: the battle for mRNA stability enters the coding sequence. Mol Cell. 35(2):139-40 (abstract)
 
Siegel, G., Obernosterer, G., Fiore, R., Oehmen, M., Bicker, S., Christensen, M., Khudayberdiev, S., Leuschner, PF., Busch, CJ., Kane, C., Hübel, K., Dekker, F., Hedberg, C., Rengarajan, B., Drepper, C., Waldmann, H., Kauppinen, S., Greenberg, ME., Draguhn, A., Rehmsmeier, M., Martinez, J., Schratt, GM. (2009). A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol. 11(6):705-16 (abstract)
 
(2008)
 
Gebeshuber, C., Salvá Giró, A., Martinez, J. (2008). MicroRNAs and their impact on tumor initiation and progression. In: Human Epithelial Tumor Cell Plasticity: Implications for Cancer Progression and Metastasis. Ed. Paul J. Higgins. p:103
 
Martinez, J., Neugebauer, KM. (2008). El Sur también existe: processing RNA in the Argentine Patagonia. Meetings on 'Cell Biology, Signaling and Alternative Splicing' and 'Gene Expression and RNA Processing'. EMBO Rep. 9(6):516-20 (abstract)
 
Obernosterer, G., Tafer, H., Martinez, J. (2008). Target site effects in the RNA interference and microRNA pathways. Biochem Soc Trans. 36(Pt 6):1216-9 (abstract)
 
Tafer, H., Ameres, SL., Obernosterer, G., Gebeshuber, CA., Schroeder, R., Martinez, J., Hofacker, IL. (2008). The impact of target site accessibility on the design of effective siRNAs. Nat Biotechnol. 26(5):578-83 (abstract)
 
(2007)
 
Ameres, SL., Martinez, J., Schroeder, R. (2007). Molecular basis for target RNA recognition and cleavage by human RISC. Cell. 130(1):101-12 (abstract)
 
Leuschner, PJ., Martinez, J. (2007). In vitro analysis of microRNA processing using recombinant Dicer and cytoplasmic extracts of HeLa cells. Methods. 43(2):105-9 (abstract)
 
Martinez, J., Busslinger, M. (2007). Life beyond cleavage: the case of Ago2 and hematopoiesis. Genes Dev. 21(16):1983-8 (abstract)
 
Nielsen, AF., Leuschner, PJ., Martinez, J. (2007). Not miR-ly a splicing factor: hnRNP A1 succumbs to microRNA temptation. Nat Struct Mol Biol. 14(7):572-3 (abstract)
 
Obernosterer, G., Martinez, J., Alenius, M. (2007). Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat Protoc. 2(6):1508-14 (abstract)
 
Obernosterer, G., Meister, G., Poy, MN., Kuras, A. (2007). The impact of small RNAs. Microsymposium on small RNAs. EMBO Rep. 8(1):23-7 (abstract)
 
Weitzer, S., Martinez, J. (2007). The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs. Nature. 447(7141):222-6 (abstract)
 
Weitzer, S., Martinez, J. (2007). hClp1: a novel kinase revitalizes RNA metabolism. Cell Cycle. 6(17):2133-7 (abstract)
 
(2006)
 
Leuschner, PJ., Ameres, SL., Kueng, S., Martinez, J. (2006). Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Rep. 7(3):314-20 (abstract)
 
Obernosterer, G., Leuschner, PJ., Alenius, M., Martinez, J. (2006). Post-transcriptional regulation of microRNA expression. RNA. 12(7):1161-7 (abstract)
 
(2005)
 
Leuschner, PJ., Obernosterer, G., Martinez, J. (2005). MicroRNAs: Loquacious speaks out. Curr Biol. 15(15):R603-5 (abstract)
 
(2004)
 
Martinez, J., Tuschl, T. (2004). RISC is a 5' phosphomonoester-producing RNA endonuclease. Genes Dev. 18(9):975-80 (abstract)