2013

Ameres, SL., Zamore, PD. (2013). Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol. 14(8):475-88 (abstract)
 
Badger-Brown, KM., Gillis, LC., Bailey, ML., Penninger, JM., Barber, DL. (2013). CBL-B is required for leukemogenesis mediated by BCR-ABL through negative regulation of bone marrow homing. Leukemia. 27(5):1146-54 (abstract)
 
Bardet, AF., Steinmann, J., Bafna, S., Knoblich, JA., Zeitlinger, J., Stark, A. (2013). Identification of transcription factor binding sites from ChIP-seq data at high resolution. Bioinformatics. 29(21):2705-13 (abstract)
 
Chalker, DL., Meyer, E., Mochizuki, K. (2013). Epigenetics of ciliates. Cold Spring Harb Perspect Biol. 5(12):a017764 (abstract)
 
Dang, I., Gorelik, R., Sousa-Blin, C., Derivery, E., Guérin, C., Linkner, J., Nemethova, M., Dumortier, JG., Giger, FA., Chipysheva, TA., Ermilova, VD., Vacher, S., Campanacci, V., Herrada, I., Planson, AG., Fetics, S., Henriot, V., David, V., Oguievetskaia, K., Lakisic, G., Pierre, F., Steffen, A., Boyreau, A., Peyriéras, N., Rottner, K., Zinn-Justin, S., Cherfils, J., Bièche, I., Alexandrova, AY., David, NB., Small, JV., Faix, J., Blanchoin, L., Gautreau, A. (2013). Inhibitory signalling to the Arp2/3 complex steers cell migration. Nature. 503(7475):281-4 (abstract)
 
Daugaard, M., Nitsch, R., Razaghi, B., McDonald, L., Jarrar, A., Torrino, S., Castillo-Lluva, S., Rotblat, B., Li, L., Malliri, A., Lemichez, E., Mettouchi, A., Berman, JN., Penninger, JM., Sorensen, PH. (2013). Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes. Nat Commun. 4:2180 (abstract)
 
Dick, AE., Gerlich, DW. (2013). Kinetic framework of spindle assembly checkpoint signalling. Nat Cell Biol. 15(11):1370-7 (abstract)
 
Dönertas, D., Sienski, G., Brennecke, J. (2013). Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex. Genes Dev. 27(15):1693-705 (abstract)
 
Earnshaw, WC., Allshire, RC., Black, BE., Bloom, K., Brinkley, BR., Brown, W., Cheeseman, IM., Choo, KH., Copenhaver, GP., Deluca, JG., Desai, A., Diekmann, S., Erhardt, S., Fitzgerald-Hayes, M., Foltz, D., Fukagawa, T., Gassmann, R., Gerlich, DW., Glover, DM., Gorbsky, GJ., Harrison, SC., Heun, P., Hirota, T., Jansen, LE., Karpen, G., Kops, GJ., Lampson, MA., Lens, SM., Losada, A., Luger, K., Maiato, H., Maddox, PS., Margolis, RL., Masumoto, H., McAinsh, AD., Mellone, BG., Meraldi, P., Musacchio, A., Oegema, K., O'Neill, RJ., Salmon, ED., Scott, KC., Straight, AF., Stukenberg, PT., Sullivan, BA., Sullivan, KF., Sunkel, CE., Swedlow, JR., Walczak, CE., Warburton, PE., Westermann, S., Willard, HF., Wordeman, L., Yanagida, M., Yen, TJ., Yoda, K., Cleveland, DW. (2013). Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 21(2):101-6 (abstract)
 
Elsayad, K., Urich, A., Tan, PS., Nemethova, M., Small, JV., Unterrainer, K., Heinze, KG. (2013). Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates. Proc Natl Acad Sci U S A. 110(50):20069-74 (abstract)
 
Fielding, RA., Gunstad, J., Gustafson, DR., Heymsfield, SB., Kral, JG., Launer, LJ., Penninger, J., Phillips, DI., Scarmeas, N. (2013). The paradox of overnutrition in aging and cognition. Ann N Y Acad Sci. 1287:31-43 (abstract)
 
Frese, CK., Zhou, H., Taus, T., Altelaar, AF., Mechtler, K., Heck, AJ., Mohammed, S. (2013). Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD). J Proteome Res. 12(3):1520-5 (abstract)
 
Furuya, Y., Inagaki, A., Khan, M., Mori, K., Penninger, JM., Nakamura, M., Udagawa, N., Aoki, K., Ohya, K., Uchida, K., Yasuda, H. (2013). Stimulation of bone formation in cortical bone of mice treated with a receptor activator of nuclear factor-κB ligand (RANKL)-binding peptide that possesses osteoclastogenesis inhibitory activity. J Biol Chem. 288(8):5562-71 (abstract)
 
Gebeshuber, CA., Kornauth, C., Dong, L., Sierig, R., Seibler, J., Reiss, M., Tauber, S., Bilban, M., Wang, S., Kain, R., Böhmig, GA., Moeller, MJ., Gröne, HJ., Englert, C., Martinez, J., Kerjaschki, D. (2013). Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1. Nat Med. 19(4):481-7 (abstract)
 
Gebeshuber, CA., Martinez, J. (2013). miR-100 suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling. Oncogene. 32(27):3306-10 (abstract)
 
Hanada, T., Weitzer, S., Mair, B., Bernreuther, C., Wainger, BJ., Ichida, J., Hanada, R., Orthofer, M., Cronin, SJ., Komnenovic, V., Minis, A., Sato, F., Mimata, H., Yoshimura, A., Tamir, I., Rainer, J., Kofler, R., Yaron, A., Eggan, KC., Woolf, CJ., Glatzel, M., Herbst, R., Martinez, J., Penninger, JM. (2013). CLP1 links tRNA metabolism to progressive motor-neuron loss. Nature. 495(7442):474-80 (abstract)
 
Handler, D., Meixner, K., Pizka, M., Lauss, K., Schmied, C., Gruber, FS., Brennecke, J. (2013). The genetic makeup of the Drosophila piRNA pathway. Mol Cell. 50(5):762-77 (abstract)
 
Harzer, H., Berger, C., Conder, R., Schmauss, G., Knoblich, JA. (2013). FACS purification of Drosophila larval neuroblasts for next-generation sequencing. Nat Protoc. 8(6):1088-99 (abstract)
 
Haschke, M., Schuster, M., Poglitsch, M., Loibner, H., Salzberg, M., Bruggisser, M., Penninger, J., Krähenbühl, S. (2013). Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects. Clin Pharmacokinet. 52(9):783-92 (abstract)
 
Homem, CC., Reichardt, I., Berger, C., Lendl, T., Knoblich, JA. (2013). Long-term live cell imaging and automated 4D analysis of drosophila neuroblast lineages. PLoS One. 8(11):e79588 (abstract)
 
Ichikawa, A., Kuba, K., Morita, M., Chida, S., Tezuka, H., Hara, H., Sasaki, T., Ohteki, T., Ranieri, VM., dos Santos, CC., Kawaoka, Y., Akira, S., Luster, AD., Lu, B., Penninger, JM., Uhlig, S., Slutsky, AS., Imai, Y. (2013). CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. Am J Respir Crit Care Med. 187(1):65-77 (abstract)
 
Ikeda, F., Lahav, G. (2013). Signal transduction and signaling networks. Mol Biol Cell. 24(6):676 (abstract)
 
Ivanov, AR., Colangelo, CM., Dufresne, CP., Friedman, DB., Lilley, KS., Mechtler, K., Phinney, BS., Rose, KL., Rudnick, PA., Searle, BC., Shaffer, SA., Weintraub, ST. (2013). Interlaboratory studies and initiatives developing standards for proteomics. Proteomics. 13(6):904-9 (abstract)
 
Jüschke, C., Dohnal, I., Pichler, P., Harzer, H., Swart, R., Ammerer, G., Mechtler, K., Knoblich, JA. (2013). Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation. Genome Biol. 14(11):r133 (abstract)
 
Jux, B., Staratschek-Jox, A., Penninger, JM., Schultze, JL., Kolanus, W. (2013). Vav1 regulates MHCII expression in murine resting and activated B cells. Int Immunol. 25(5):307-17 (abstract)
 
Kiechl, S., Wittmann, J., Giaccari, A., Knoflach, M., Willeit, P., Bozec, A., Moschen, AR., Muscogiuri, G., Sorice, GP., Kireva, T., Summerer, M., Wirtz, S., Luther, J., Mielenz, D., Billmeier, U., Egger, G., Mayr, A., Oberhollenzer, F., Kronenberg, F., Orthofer, M., Penninger, JM., Meigs, JB., Bonora, E., Tilg, H., Willeit, J., Schett, G. (2013). Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus. Nat Med. 19(3):358-63 (abstract)
 
Koestler, SA., Steffen, A., Nemethova, M., Winterhoff, M., Luo, N., Holleboom, JM., Krupp, J., Jacob, S., Vinzenz, M., Schur, F., Schlüter, K., Gunning, PW., Winkler, C., Schmeiser, C., Faix, J., Stradal, TE., Small, JV., Rottner, K. (2013). Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin. Mol Biol Cell. 24(18):2861-75 (abstract)
 
Kuba, K., Imai, Y., Penninger, JM. (2013). Multiple functions of angiotensin-converting enzyme 2 and its relevance in cardiovascular diseases. Circ J. 77(2):301-8 (abstract)
 
Lancaster, MA., Renner, M., Martin, CA., Wenzel, D., Bicknell, LS., Hurles, ME., Homfray, T., Penninger, JM., Jackson, AP., Knoblich, JA. (2013). Cerebral organoids model human brain development and microcephaly. Nature. 501(7467):373-9 (abstract)
 
Lauwers, M., Pichler, P., Edelman, NB., Resch, GP., Ushakova, L., Salzer, MC., Heyers, D., Saunders, M., Shaw, J., Keays, DA. (2013). An iron-rich organelle in the cuticular plate of avian hair cells. Curr Biol. 23(10):924-9 (abstract)
 
Lee, HJ., Gallego-Ortega, D., Ledger, A., Schramek, D., Joshi, P., Szwarc, MM., Cho, C., Lydon, JP., Khokha, R., Penninger, JM., Ormandy, CJ. (2013). Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells. Development. 140(7):1397-401 (abstract)
 
Lo, J., Patel, VB., Wang, Z., Levasseur, J., Kaufman, S., Penninger, JM., Oudit, GY. (2013). Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats. Exp Physiol. 98(1):109-22 (abstract)
 
Mair, B., Popow, J., Mechtler, K., Weitzer, S., Martinez, J. (2013). Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components. Biochem Soc Trans. 41(4):831-7 (abstract)
 
Malvezzi, F., Litos, G., Schleiffer, A., Heuck, A., Mechtler, K., Clausen, T., Westermann, S. (2013). A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO J. 32(3):409-23 (abstract)
 
Medvedovic, J., Ebert, A., Tagoh, H., Tamir, IM., Schwickert, TA., Novatchkova, M., Sun, Q., Huis In 't Veld, PJ., Guo, C., Yoon, HS., Denizot, Y., Holwerda, SJ., de Laat, W., Cogné, M., Shi, Y., Alt, FW., Busslinger, M. (2013). Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity. 39(2):229-44 (abstract)
 
Mochizuki, K., Kurth, HM. (2013). Loading and pre-loading processes generate a distinct siRNA population in Tetrahymena. Biochem Biophys Res Commun. 436(3):497-502 (abstract)
 
Morita, M., Kuba, K., Ichikawa, A., Nakayama, M., Katahira, J., Iwamoto, R., Watanebe, T., Sakabe, S., Daidoji, T., Nakamura, S., Kadowaki, A., Ohto, T., Nakanishi, H., Taguchi, R., Nakaya, T., Murakami, M., Yoneda, Y., Arai, H., Kawaoka, Y., Penninger, JM., Arita, M., Imai, Y. (2013). The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza. Cell. 153(1):112-25 (abstract)
 
Moruz, L., Pichler, P., Stranzl, T., Mechtler, K., Käll, L. (2013). Optimized nonlinear gradients for reversed-phase liquid chromatography in shotgun proteomics. Anal Chem. 85(16):7777-85 (abstract)
 
Nishiyama, T., Sykora, MM., Huis in 't Veld, PJ., Mechtler, K., Peters, JM. (2013). Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin. Proc Natl Acad Sci U S A. 110(33):13404-9 (abstract)
 
Offord, EA., Karagounis, LG., Vidal, K., Fielding, R., Meydani, S., Penninger, JM. (2013). Nutrition and the biology of human ageing: bone health and osteoporosis / sarcopenia / immune deficiency. J Nutr Health Aging. 17(8):712-6 (abstract)
 
Osman, K., Roitinger, E., Yang, J., Armstrong, S., Mechtler, K., Franklin, FC. (2013). Analysis of meiotic protein complexes from Arabidopsis and Brassica using affinity-based proteomics. Methods Mol Biol. 990:215-26 (abstract)
 
Paul, DS., Albers, CA., Rendon, A., Voss, K., Stephens, J., van der Harst, P., Chambers, JC., Soranzo, N., Ouwehand, WH., Deloukas, P. (2013). Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res. 23(7):1130-41 (abstract)
 
Perlot, T., Penninger, JM. (2013). ACE2 - from the renin-angiotensin system to gut microbiota and malnutrition. Microbes Infect. 15(13):866-73 (abstract)
 
Raith, M., Valencia, RG., Fischer, I., Orthofer, M., Penninger, JM., Spuler, S., Rezniczek, GA., Wiche, G. (2013). Linking cytoarchitecture to metabolism: sarcolemma-associated plectin affects glucose uptake by destabilizing microtubule networks in mdx myofibers. Skelet Muscle. 3(1):14 (abstract)
 
Reichardt, I., Knoblich, JA. (2013). Cell biology: Notch recycling is numbed. Curr Biol. 23(7):R270-2 (abstract)
 
Reiter, W., Klopf, E., De Wever, V., Anrather, D., Petryshyn, A., Roetzer, A., Niederacher, G., Roitinger, E., Dohnal, I., Görner, W., Mechtler, K., Brocard, C., Schüller, C., Ammerer, G. (2013). Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment. Mol Cell Biol. 33(5):1057-72 (abstract)
 
Samwer, M., Dehne, HJ., Spira, F., Kollmar, M., Gerlich, DW., Urlaub, H., Görlich, D. (2013). The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J. 32(13):1886-902 (abstract)
 
Sato, T., Suzuki, T., Watanabe, H., Kadowaki, A., Fukamizu, A., Liu, PP., Kimura, A., Ito, H., Penninger, JM., Imai, Y., Kuba, K. (2013). Apelin is a positive regulator of ACE2 in failing hearts. J Clin Invest. 123(12):5203-11 (abstract)
 
Schmidt, A., Ammerer, G., Mechtler, K. (2013). Studying the fragmentation behavior of peptides with arginine phosphorylation and its influence on phospho-site localization. Proteomics. 13(6):945-54 (abstract)
 
Simunovic, M., Mim, C., Marlovits, TC., Resch, G., Unger, VM., Voth, GA. (2013). Protein-mediated transformation of lipid vesicles into tubular networks. Biophys J. 105(3):711-9 (abstract)
 
Sommer, C., Gerlich, DW. (2013). Machine learning in cell biology - teaching computers to recognize phenotypes. J Cell Sci. 126(Pt 24):5529-39 (abstract)
 
Sommer, C., Held, M., Fischer, B., Huber, W., Gerlich, DW. (2013). CellH5: a format for data exchange in high-content screening. Bioinformatics. 29(12):1580-2 (abstract)
 
Song, B., Jin, H., Yu, X., Zhang, Z., Yu, H., Ye, J., Xu, Y., Zhou, T., Oudit, GY., Ye, JY., Chen, C., Gao, P., Zhu, D., Penninger, JM., Zhong, JC. (2013). Angiotensin-converting enzyme 2 attenuates oxidative stress and VSMC proliferation via the JAK2/STAT3/SOCS3 and profilin-1/MAPK signaling pathways. Regul Pept. 185:44-51 (abstract)
 
Sparmann, A., Xie, Y., Verhoeven, E., Vermeulen, M., Lancini, C., Gargiulo, G., Hulsman, D., Mann, M., Knoblich, JA., van Lohuizen, M. (2013). The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J. 32(11):1598-612 (abstract)
 
Steffen, A., Ladwein, M., Dimchev, GA., Hein, A., Schwenkmezger, L., Arens, S., Ladwein, KI., Margit Holleboom, J., Schur, F., Victor Small, J., Schwarz, J., Gerhard, R., Faix, J., Stradal, TE., Brakebusch, C., Rottner, K. (2013). Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation. J Cell Sci. 126(Pt 20):4572-88 (abstract)
 
Steffen, PA., Fonseca, JP., Gänger, C., Dworschak, E., Kockmann, T., Beisel, C., Ringrose, L. (2013). Quantitative in vivo analysis of chromatin binding of Polycomb and Trithorax group proteins reveals retention of ASH1 on mitotic chromatin. Nucleic Acids Res. 41(10):5235-50 (abstract)
 
Tachibana-Konwalski, K., Godwin, J., Borsos, M., Rattani, A., Adams, DJ., Nasmyth, K. (2013). Spindle assembly checkpoint of oocytes depends on a kinetochore structure determined by cohesin in meiosis I. Curr Biol. 23(24):2534-9 (abstract)
 
Uehara, R., Tsukada, Y., Kamasaki, T., Poser, I., Yoda, K., Gerlich, DW., Goshima, G. (2013). Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase. J Cell Biol. 202(4):623-36 (abstract)
 
Vogt, A., Goldman, AD., Mochizuki, K., Landweber, LF. (2013). Transposon domestication versus mutualism in ciliate genome rearrangements. PLoS Genet. 9(8):e1003659 (abstract)
 
Vogt, A., Mochizuki, K. (2013). A domesticated PiggyBac transposase interacts with heterochromatin and catalyzes reproducible DNA elimination in Tetrahymena. PLoS Genet. 9(12):e1004032 (abstract)
 
Wallner, S., Lutz-Nicoladoni, C., Tripp, CH., Gastl, G., Baier, G., Penninger, JM., Stoitzner, P., Wolf, D. (2013). The role of the e3 ligase cbl-B in murine dendritic cells. PLoS One. 8(6):e65178 (abstract)
 
Wang, W., McKinnie, SM., Patel, VB., Haddad, G., Wang, Z., Zhabyeyev, P., Das, SK., Basu, R., McLean, B., Kandalam, V., Penninger, JM., Kassiri, Z., Vederas, JC., Murray, AG., Oudit, GY. (2013). Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. J Am Heart Assoc. 2(4):e000249 (abstract)
 
Wang, W., Yang, P., Zhong, Y., Zhao, Z., Xing, L., Zhao, Y., Zou, Z., Zhang, Y., Li, C., Li, T., Wang, C., Wang, Z., Yu, X., Cao, B., Gao, X., Penninger, JM., Wang, X., Jiang, C. (2013). Monoclonal antibody against CXCL-10/IP-10 ameliorates influenza A (H1N1) virus induced acute lung injury. Cell Res. 23(4):577-80 (abstract)
 
Westermann, S., Schleiffer, A. (2013). Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans. Trends Cell Biol. 23(6):260-9 (abstract)
 
Wöhrle, FU., Halbach, S., Aumann, K., Schwemmers, S., Braun, S., Auberger, P., Schramek, D., Penninger, JM., Laßmann, S., Werner, M., Waller, CF., Pahl, HL., Zeiser, R., Daly, RJ., Brummer, T. (2013). Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors. Leukemia. 27(1):118-29 (abstract)
 
Xie, Y., Jüschke, C., Esk, C., Hirotsune, S., Knoblich, JA. (2013). The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron. 79(2):254-65 (abstract)
 
Zhang, ZZ., Shang, QH., Jin, HY., Song, B., Oudit, GY., Lu, L., Zhou, T., Xu, YL., Gao, PJ., Zhu, DL., Penninger, JM., Zhong, JC. (2013). Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice. J Transl Med. 11:229 (abstract)
 

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