2011

Alexander, J., Lim, D., Joughin, BA., Hegemann, B., Hutchins, JR., Ehrenberger, T., Ivins, F., Sessa, F., Hudecz, O., Nigg, EA., Fry, AM., Musacchio, A., Stukenberg, PT., Mechtler, K., Peters, JM., Smerdon, SJ., Yaffe, MB. (2011). Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal. 4(179):ra42 (abstract)
 
Bodiga, S., Zhong, JC., Wang, W., Basu, R., Lo, J., Liu, GC., Guo, D., Holland, SM., Scholey, JW., Penninger, JM., Kassiri, Z., Oudit, GY. (2011). Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit. Cardiovasc Res. 91(1):151-61 (abstract)
 
Böhmdorfer, G., Schleiffer, A., Brunmeir, R., Ferscha, S., Nizhynska, V., Kozák, J., Angelis, KJ., Kreil, DP., Schweizer, D. (2011). GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis. Plant J. 67(3):420-33 (abstract)
 
Breitsprecher, D., Kiesewetter, AK., Linkner, J., Vinzenz, M., Stradal, TE., Small, JV., Curth, U., Dickinson, RB., Faix, J. (2011). Molecular mechanism of Ena/VASP-mediated actin-filament elongation. EMBO J. 30(3):456-67 (abstract)
 
Breitsprecher, D., Koestler, SA., Chizhov, I., Nemethova, M., Mueller, J., Goode, BL., Small, JV., Rottner, K., Faix, J. (2011). Cofilin cooperates with fascin to disassemble filopodial actin filaments. J Cell Sci. 124(Pt 19):3305-18 (abstract)
 
Breitwieser, FP., Müller, A., Dayon, L., Köcher, T., Hainard, A., Pichler, P., Schmidt-Erfurth, U., Superti-Furga, G., Sanchez, JC., Mechtler, K., Bennett, KL., Colinge, J. (2011). General statistical modeling of data from protein relative expression isobaric tags. J Proteome Res. 10(6):2758-66 (abstract)
 
Duheron, V., Hess, E., Duval, M., Decossas, M., Castaneda, B., Klöpper, JE., Amoasii, L., Barbaroux, JB., Williams, IR., Yagita, H., Penninger, J., Choi, Y., Lézot, F., Groves, R., Paus, R., Mueller, CG. (2011). Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proc Natl Acad Sci U S A. 108(13):5342-7 (abstract)
 
Ebert, A., McManus, S., Tagoh, H., Medvedovic, J., Salvagiotto, G., Novatchkova, M., Tamir, I., Sommer, A., Jaritz, M., Busslinger, M. (2011). The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity. 34(2):175-87 (abstract)
 
Elling, U., Taubenschmid, J., Wirnsberger, G., O'Malley, R., Demers, SP., Vanhaelen, Q., Shukalyuk, AI., Schmauss, G., Schramek, D., Schnuetgen, F., von Melchner, H., Ecker, JR., Stanford, WL., Zuber, J., Stark, A., Penninger, JM. (2011). Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. Cell Stem Cell. 9(6):563-74 (abstract)
 
Fischer, H., Szabo, S., Scherz, J., Jaeger, K., Rossiter, H., Buchberger, M., Ghannadan, M., Hermann, M., Theussl, HC., Tobin, DJ., Wagner, EF., Tschachler, E., Eckhart, L. (2011). Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails. J Invest Dermatol. 131(6):1208-15 (abstract)
 
Gieger, C., Radhakrishnan, A., Cvejic, A., Tang, W., Porcu, E., Pistis, G., Serbanovic-Canic, J., Elling, U., Goodall, AH., Labrune, Y., Lopez, LM., Mägi, R., Meacham, S., Okada, Y., Pirastu, N., Sorice, R., Teumer, A., Voss, K., Zhang, W., Ramirez-Solis, R., Bis, JC., Ellinghaus, D., Gögele, M., Hottenga, JJ., Langenberg, C., Kovacs, P., O'Reilly, PF., Shin, SY., Esko, T., Hartiala, J., Kanoni, S., Murgia, F., Parsa, A., Stephens, J., van der Harst, P., Ellen van der Schoot, C., Allayee, H., Attwood, A., Balkau, B., Bastardot, F., Basu, S., Baumeister, SE., Biino, G., Bomba, L., Bonnefond, A., Cambien, F., Chambers, JC., Cucca, F., D'Adamo, P., Davies, G., de Boer, RA., de Geus, EJ., Döring, A., Elliott, P., Erdmann, J., Evans, DM., Falchi, M., Feng, W., Folsom, AR., Frazer, IH., Gibson, QD., Glazer, NL., Hammond, C., Hartikainen, AL., Heckbert, SR., Hengstenberg, C., Hersch, M., Illig, T., Loos, RJ., Jolley, J., Khaw, KT., Kühnel, B., Kyrtsonis, MC., Lagou, V., Lloyd-Jones, H., Lumley, T., Mangino, M., Maschio, A., Mateo Leach, I., McKnight, B., Memari, Y., Mitchell, BD., Montgomery, GW., Nakamura, Y., Nauck, M., Navis, G., Nöthlings, U., Nolte, IM., Porteous, DJ., Pouta, A., Pramstaller, PP., Pullat, J., Ring, SM., Rotter, JI., Ruggiero, D., Ruokonen, A., Sala, C., Samani, NJ., Sambrook, J., Schlessinger, D., Schreiber, S., Schunkert, H., Scott, J., Smith, NL., Snieder, H., Starr, JM., Stumvoll, M., Takahashi, A., Tang, WH., Taylor, K., Tenesa, A., Lay Thein, S., Tönjes, A., Uda, M., Ulivi, S., van Veldhuisen, DJ., Visscher, PM., Völker, U., Wichmann, HE., Wiggins, KL., Willemsen, G., Yang, TP., Hua Zhao, J., Zitting, P., Bradley, JR., Dedoussis, GV., Gasparini, P., Hazen, SL., Metspalu, A., Pirastu, M., Shuldiner, AR., Joost van Pelt, L., Zwaginga, JJ., Boomsma, DI., Deary, IJ., Franke, A., Froguel, P., Ganesh, SK., Jarvelin, MR., Martin, NG., Meisinger, C., Psaty, BM., Spector, TD., Wareham, NJ., Akkerman, JW., Ciullo, M., Deloukas, P., Greinacher, A., Jupe, S., Kamatani, N., Khadake, J., Kooner, JS., Penninger, J., Prokopenko, I., Stemple, D., Toniolo, D., Wernisch, L., Sanna, S., Hicks, AA., Rendon, A., Ferreira, MA., Ouwehand, WH., Soranzo, N. (2011). New gene functions in megakaryopoiesis and platelet formation. Nature. 480(7376):201-8 (abstract)
 
Grosstessner-Hain, K., Hegemann, B., Novatchkova, M., Rameseder, J., Joughin, BA., Hudecz, O., Roitinger, E., Pichler, P., Kraut, N., Yaffe, MB., Peters, JM., Mechtler, K. (2011). Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome. Mol Cell Proteomics. 10(11):M111.008540 (abstract)
 
Hanada, R., Hanada, T., Sigl, V., Schramek, D., Penninger, JM. (2011). RANKL/RANK-beyond bones. J Mol Med (Berl). 89(7):647-56 (abstract)
 
Hanada, R., Penninger, JM. (2011). [Central regulation of body temperature by RANKL/RANK pathway]. Clin Calcium. 21(8):1201-8 (abstract)
 
Handler, D., Olivieri, D., Novatchkova, M., Gruber, FS., Meixner, K., Mechtler, K., Stark, A., Sachidanandam, R., Brennecke, J. (2011). A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. EMBO J. 30(19):3977-93 (abstract)
 
Hasanovic, A., Winkler, R., Resch, GP., Valenta, C. (2011). Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir. Eur J Pharm Biopharm. 79(1):76-81 (abstract)
 
Hegemann, B., Hutchins, JR., Hudecz, O., Novatchkova, M., Rameseder, J., Sykora, MM., Liu, S., Mazanek, M., Lénárt, P., Hériché, JK., Poser, I., Kraut, N., Hyman, AA., Yaffe, MB., Mechtler, K., Peters, JM. (2011). Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal. 4(198):rs12 (abstract)
 
Heuck, A., Schleiffer, A., Clausen, T. (2011). Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins. J Mol Biol. 406(5):659-66 (abstract)
 
Holzmann, J., Fuchs, J., Pichler, P., Peters, JM., Mechtler, K. (2011). Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads. J Proteome Res. 10(2):780-9 (abstract)
 
Huang, R., Jaritz, M., Guenzl, P., Vlatkovic, I., Sommer, A., Tamir, IM., Marks, H., Klampfl, T., Kralovics, R., Stunnenberg, HG., Barlow, DP., Pauler, FM. (2011). An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs. PLoS One. 6(11):e27288 (abstract)
 
Jin, R., Song, Z., Yu, S., Piazza, A., Nanda, A., Penninger, JM., Granger, DN., Li, G. (2011). Phosphatidylinositol-3-kinase gamma plays a central role in blood-brain barrier dysfunction in acute experimental stroke. Stroke. 42(7):2033-44 (abstract)
 
Kaminski, S., Hermann-Kleiter, N., Meisel, M., Thuille, N., Cronin, S., Hara, H., Fresser, F., Penninger, JM., Baier, G. (2011). Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells. J Autoimmun. 37(3):198-208 (abstract)
 
Kataoka, K., Mochizuki, K. (2011). Programmed DNA elimination in Tetrahymena: a small RNA-mediated genome surveillance mechanism. Adv Exp Med Biol. 722:156-73 (abstract)
 
Khan, AG., Pickl-Herk, A., Gajdzik, L., Marlovits, TC., Fuchs, R., Blaas, D. (2011). Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin. Virology. 412(1):55-67 (abstract)
 
Khazaei, MR., Bunk, EC., Hillje, AL., Jahn, HM., Riegler, EM., Knoblich, JA., Young, P., Schwamborn, JC. (2011). The E3-ubiquitin ligase TRIM2 regulates neuronal polarization. J Neurochem. 117(1):29-37 (abstract)
 
Köcher, T., Pichler, P., Mazanek, M., Swart, R., Mechtler, K. (2011). Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications. Anal Bioanal Chem. 400(8):2339-47 (abstract)
 
Köcher, T., Pichler, P., Swart, R., Mechtler, K. (2011). Quality control in LC-MS/MS. Proteomics. 11(6):1026-30 (abstract)
 
Köcher, T., Swart, R., Mechtler, K. (2011). Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides. Anal Chem. 83(7):2699-704 (abstract)
 
Koletar, MM., Cheng, HY., Penninger, JM., Ralph, MR. (2011). Loss of dexras1 alters nonphotic circadian phase shifts and reveals a role for the intergeniculate leaflet (IGL) in gene-targeted mice. Chronobiol Int. 28(7):553-62 (abstract)
 
Kornfeld, JW., Isaacs, A., Vitart, V., Pospisilik, JA., Meitinger, T., Gyllensten, U., Wilson, JF., Rudan, I., Campbell, H., Penninger, JM., Sexl, V., Moriggl, R., van Duijn, C., Pramstaller, PP., Hicks, AA. (2011). Variants in STAT5B associate with serum TC and LDL-C levels. J Clin Endocrinol Metab. 96(9):E1496-501 (abstract)
 
Kramer, JM., Kochinke, K., Oortveld, MA., Marks, H., Kramer, D., de Jong, EK., Asztalos, Z., Westwood, JT., Stunnenberg, HG., Sokolowski, MB., Keleman, K., Zhou, H., van Bokhoven, H., Schenck, A. (2011). Epigenetic regulation of learning and memory by Drosophila EHMT/G9a. PLoS Biol. 9(1):e1000569 (abstract)
 
Lee, AW., Mao, Y., Penninger, JM., Yu, S. (2011). Gab2 promotes colony-stimulating factor 1-regulated macrophage expansion via alternate effectors at different stages of development. Mol Cell Biol. 31(22):4563-81 (abstract)
 
Leibbrandt, A., Penninger, JM. (2011). TNF conference 2009: beyond bones - RANKL/RANK in the immune system. Adv Exp Med Biol. 691:5-22 (abstract)
 
Meng, X., Arocena, M., Penninger, J., Gage, FH., Zhao, M., Song, B. (2011). PI3K mediated electrotaxis of embryonic and adult neural progenitor cells in the presence of growth factors. Exp Neurol. 227(1):210-7 (abstract)
 
Miyamoto, K., Yoshida, S., Kawasumi, M., Hashimoto, K., Kimura, T., Sato, Y., Kobayashi, T., Miyauchi, Y., Hoshi, H., Iwasaki, R., Miyamoto, H., Hao, W., Morioka, H., Chiba, K., Kobayashi, T., Yasuda, H., Penninger, JM., Toyama, Y., Suda, T., Miyamoto, T. (2011). Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization. J Exp Med. 208(11):2175-81 (abstract)
 
Mouri, Y., Yano, M., Shinzawa, M., Shimo, Y., Hirota, F., Nishikawa, Y., Nii, T., Kiyonari, H., Abe, T., Uehara, H., Izumi, K., Tamada, K., Chen, L., Penninger, JM., Inoue, J., Akiyama, T., Matsumoto, M. (2011). Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma. J Immunol. 186(9):5047-57 (abstract)
 
Muto, A., Mizoguchi, T., Udagawa, N., Ito, S., Kawahara, I., Abiko, Y., Arai, A., Harada, S., Kobayashi, Y., Nakamichi, Y., Penninger, JM., Noguchi, T., Takahashi, N. (2011). Lineage-committed osteoclast precursors circulate in blood and settle down into bone. J Bone Miner Res. 26(12):2978-90 (abstract)
 
Nakashima, T., Hayashi, M., Fukunaga, T., Kurata, K., Oh-Hora, M., Feng, JQ., Bonewald, LF., Kodama, T., Wutz, A., Wagner, EF., Penninger, JM., Takayanagi, H. (2011). Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med. 17(10):1231-4 (abstract)
 
Neely, GG., Keene, AC., Duchek, P., Chang, EC., Wang, QP., Aksoy, YA., Rosenzweig, M., Costigan, M., Woolf, CJ., Garrity, PA., Penninger, JM. (2011). TrpA1 regulates thermal nociception in Drosophila. PLoS One. 6(8):e24343 (abstract)
 
Neumüller, RA., Richter, C., Fischer, A., Novatchkova, M., Neumüller, KG., Knoblich, JA. (2011). Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 8(5):580-93 (abstract)
 
Ni, JQ., Zhou, R., Czech, B., Liu, LP., Holderbaum, L., Yang-Zhou, D., Shim, HS., Tao, R., Handler, D., Karpowicz, P., Binari, R., Booker, M., Brennecke, J., Perkins, LA., Hannon, GJ., Perrimon, N. (2011). A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nat Methods. 8(5):405-7 (abstract)
 
Oelkers, JM., Vinzenz, M., Nemethova, M., Jacob, S., Lai, FP., Block, J., Szczodrak, M., Kerkhoff, E., Backert, S., Schlüter, K., Stradal, TE., Small, JV., Koestler, SA., Rottner, K. (2011). Microtubules as platforms for assaying actin polymerization in vivo. PLoS One. 6(5):e19931 (abstract)
 
Oh, SY., Park, JU., Zheng, T., Kim, YK., Wu, F., Cho, SH., Barber, D., Penninger, J., Zhu, Z. (2011). Cbl-b regulates airway mucosal tolerance to aeroallergen. Clin Exp Allergy. 41(3):434-42 (abstract)
 
Okulski, H., Druck, B., Bhalerao, S., Ringrose, L. (2011). Quantitative analysis of polycomb response elements (PREs) at identical genomic locations distinguishes contributions of PRE sequence and genomic environment. Epigenetics Chromatin. 4:4 (abstract)
 
Oudit, GY., Penninger, JM. (2011). Recombinant human angiotensin-converting enzyme 2 as a new renin-angiotensin system peptidase for heart failure therapy. Curr Heart Fail Rep. 8(3):176-83 (abstract)
 
Paolino, M., Thien, CB., Gruber, T., Hinterleitner, R., Baier, G., Langdon, WY., Penninger, JM. (2011). Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions. J Immunol. 186(4):2138-47 (abstract)
 
Pichler, P., Köcher, T., Holzmann, J., Möhring, T., Ammerer, G., Mechtler, K. (2011). Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell. Anal Chem. 83(4):1469-74 (abstract)
 
Popow, J., Englert, M., Weitzer, S., Schleiffer, A., Mierzwa, B., Mechtler, K., Trowitzsch, S., Will, CL., Lührmann, R., Söll, D., Martinez, J. (2011). HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science. 331(6018):760-4 (abstract)
 
Postiglione, MP., Jüschke, C., Xie, Y., Haas, GA., Charalambous, C., Knoblich, JA. (2011). Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 72(2):269-84 (abstract)
 
Resch, GP., Brandstetter, M., Pickl-Herk, AM., Königsmaier, L., Wonesch, VI., Urban, E. (2011). Immersion freezing of biological specimens: rationale, principles, and instrumentation. Cold Spring Harb Protoc. 2011(7):778-82 (abstract)
 
Richter, C., Oktaba, K., Steinmann, J., Müller, J., Knoblich, JA. (2011). The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements. Nat Cell Biol. 13(9):1029-39 (abstract)
 
Schoeberl, UE., Mochizuki, K. (2011). Keeping the soma free of transposons: programmed DNA elimination in ciliates. J Biol Chem. 286(43):37045-52 (abstract)
 
Schönbauer, C., Distler, J., Jährling, N., Radolf, M., Dodt, HU., Frasch, M., Schnorrer, F. (2011). Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects. Nature. 479(7373):406-9 (abstract)
 
Schraidt, O., Marlovits, TC. (2011). Three-dimensional model of Salmonella's needle complex at subnanometer resolution. Science. 331(6021):1192-5 (abstract)
 
Schramek, D., Kotsinas, A., Meixner, A., Wada, T., Elling, U., Pospisilik, JA., Neely, GG., Zwick, RH., Sigl, V., Forni, G., Serrano, M., Gorgoulis, VG., Penninger, JM. (2011). The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression. Nat Genet. 43(3):212-9 (abstract)
 
Schramek, D., Sigl, V., Penninger, JM. (2011). RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis. Trends Endocrinol Metab. 22(5):188-94 (abstract)
 
Small, J.V., Winkler, C., Vinzenz, M. and Schmeiser, S (2011). Reply: Visualizing branched actin filaments in lamellipodia by electron tomography Nature Cell Biology. doi:10.1038/ncb2322
 
Stöger-Pollach, M., Treiber, CD., Resch, GP., Keays, DA., Ennen, I. (2011). EMCD real space maps of Magnetospirillum magnetotacticum. Micron. 42(5):456-60 (abstract)
 
Strübbe, G., Popp, C., Schmidt, A., Pauli, A., Ringrose, L., Beisel, C., Paro, R. (2011). Polycomb purification by in vivo biotinylation tagging reveals cohesin and Trithorax group proteins as interaction partners. Proc Natl Acad Sci U S A. 108(14):5572-7 (abstract)
 
Taschler, U., Radner, FP., Heier, C., Schreiber, R., Schweiger, M., Schoiswohl, G., Preiss-Landl, K., Jaeger, D., Reiter, B., Koefeler, HC., Wojciechowski, J., Theussl, C., Penninger, JM., Lass, A., Haemmerle, G., Zechner, R., Zimmermann, R. (2011). Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem. 286(20):17467-77 (abstract)
 
Taus, T., Köcher, T., Pichler, P., Paschke, C., Schmidt, A., Henrich, C., Mechtler, K. (2011). Universal and confident phosphorylation site localization using phosphoRS. J Proteome Res. 10(12):5354-62 (abstract)
 
Yamasaki, T., Kawasaki, H., Arakawa, S., Shimizu, K., Shimizu, S., Reiner, O., Okano, H., Nishina, S., Azuma, N., Penninger, JM., Katada, T., Nishina, H. (2011). Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex. J Neurosci. 31(46):16872-83 (abstract)
 
Zhong, JC., Ye, JY., Jin, HY., Yu, X., Yu, HM., Zhu, DL., Gao, PJ., Huang, DY., Shuster, M., Loibner, H., Guo, JM., Yu, XY., Xiao, BX., Gong, ZH., Penninger, JM., Oudit, GY. (2011). Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression. Regul Pept. 166(1-3):90-7 (abstract)
 
Zhong, J., Guo, D., Chen, CB., Wang, W., Schuster, M., Loibner, H., Penninger, JM., Scholey, JW., Kassiri, Z., Oudit, GY. (2011). Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2. Hypertension. 57(2):314-22 (abstract)
 

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