2009

Agrelo, R., Souabni, A., Novatchkova, M., Haslinger, C., Leeb, M., Komnenovic, V., Kishimoto, H., Gresh, L., Kohwi-Shigematsu, T., Kenner, L., Wutz, A. (2009). SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells. Dev Cell. 16(4):507-16 (abstract)
 
Bednenko, J., Noto, T., DeSouza, LV., Siu, KW., Pearlman, RE., Mochizuki, K., Gorovsky, MA. (2009). Two GW repeat proteins interact with Tetrahymena thermophila argonaute and promote genome rearrangement. Mol Cell Biol. 29(18):5020-30 (abstract)
 
Blyszczuk, P., Kania, G., Dieterle, T., Marty, RR., Valaperti, A., Berthonneche, C., Pedrazzini, T., Berger, CT., Dirnhofer, S., Matter, CM., Penninger, JM., Lüscher, TF., Eriksson, U. (2009). Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy. Circ Res. 105(9):912-20 (abstract)
 
Brehme, M., Hantschel, O., Colinge, J., Kaupe, I., Planyavsky, M., Köcher, T., Mechtler, K., Bennett, KL., Superti-Furga, G. (2009). Charting the molecular network of the drug target Bcr-Abl. Proc Natl Acad Sci U S A. 106(18):7414-9 (abstract) (fulltext)
 
Brunner, MJ., Resch, GP. (2009). Automated monitoring to reduce electron microscope downtime. Ultramicroscopy. 109(11):1389-92 (abstract)
 
Camargo, SM., Singer, D., Makrides, V., Huggel, K., Pos, KM., Wagner, CA., Kuba, K., Danilczyk, U., Skovby, F., Kleta, R., Penninger, JM., Verrey, F. (2009). Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations. Gastroenterology. 136(3):872-82 (abstract)
 
Cerqueira, FR., Morandell, S., Ascher, S., Mechtler, K., Huber, LA., Pfeifer, B., Graber, A., Tilg, B., Baumgartner, C. (2009). Improving Phosphopeptide/Protein Identification Using a New Data Mining Framework for MS/MS Spectra Preprocessing J Proteomics Bioinform. 2:150-164
 
Cipak, L., Spirek, M., Novatchkova, M., Chen, Z., Rumpf, C., Lugmayr, W., Mechtler, K., Ammerer, G., Csaszar, E., Gregan, J. (2009). An improved strategy for tandem affinity purification-tagging of Schizosaccharomyces pombe genes. Proteomics. 9(20):4825-8 (abstract)
 
Colombelli, J., Besser, A., Kress, H., Reynaud, EG., Girard, P., Caussinus, E., Haselmann, U., Small, JV., Schwarz, US., Stelzer, EH. (2009). Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization. J Cell Sci. 122(Pt 10):1665-79 (abstract)
 
Conder, R., Knoblich, JA. (2009). Fly stem cell research gets infectious. Cell. 137(7):1185-7 (abstract)
 
Coumailleau, F., Fürthauer, M., Knoblich, JA., González-Gaitán, M. (2009). Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature. 458(7241):1051-5 (abstract)
 
Cronin, SJ., Nehme, NT., Limmer, S., Liegeois, S., Pospisilik, JA., Schramek, D., Leibbrandt, A., Simoes, Rde M., Gruber, S., Puc, U., Ebersberger, I., Zoranovic, T., Neely, GG., von Haeseler, A., Ferrandon, D., Penninger, JM. (2009). Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection. Science. 325(5938):340-3 (abstract)
 
Czech, B., Zhou, R., Erlich, Y., Brennecke, J., Binari, R., Villalta, C., Gordon, A., Perrimon, N., Hannon, GJ. (2009). Hierarchical rules for Argonaute loading in Drosophila. Mol Cell. 36(3):445-56 (abstract)
 
d'Erfurth, I., Jolivet, S., Froger, N., Catrice, O., Novatchkova, M., Mercier, R. (2009). Turning meiosis into mitosis. PLoS Biol. 7(6):e1000124 (abstract)
 
Fontán-Lozano, A., Romero-Granados, R., del-Pozo-Martín, Y., Suárez-Pereira, I., Delgado-García, JM., Penninger, JM., Carrión, AM. (2009). Lack of DREAM protein enhances learning and memory and slows brain aging. Curr Biol. 19(1):54-60 (abstract)
 
Fritz, J., Strehblow, A., Taschner, A., Schopoff, S., Pasierbek, P., Jantsch, MF. (2009). RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1. Mol Cell Biol. 29(6):1487-97 (abstract)
 
Fuhrmann, J., Schmidt, A., Spiess, S., Lehner, A., Turgay, K., Mechtler, K., Charpentier, E., Clausen, T. (2009). McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR. Science. 324(5932):1323-7 (abstract) (fulltext)
 
Galluzzi, L., Aaronson, SA., Abrams, J., Alnemri, ES., Andrews, DW., Baehrecke, EH., Bazan, NG., Blagosklonny, MV., Blomgren, K., Borner, C., Bredesen, DE., Brenner, C., Castedo, M., Cidlowski, JA., Ciechanover, A., Cohen, GM., De Laurenzi, V., De Maria, R., Deshmukh, M., Dynlacht, BD., El-Deiry, WS., Flavell, RA., Fulda, S., Garrido, C., Golstein, P., Gougeon, ML., Green, DR., Gronemeyer, H., Hajnóczky, G., Hardwick, JM., Hengartner, MO., Ichijo, H., Jäättelä, M., Kepp, O., Kimchi, A., Klionsky, DJ., Knight, RA., Kornbluth, S., Kumar, S., Levine, B., Lipton, SA., Lugli, E., Madeo, F., Malomi, W., Marine, JC., Martin, SJ., Medema, JP., Mehlen, P., Melino, G., Moll, UM., Morselli, E., Nagata, S., Nicholson, DW., Nicotera, P., Nuñez, G., Oren, M., Penninger, J., Pervaiz, S., Peter, ME., Piacentini, M., Prehn, JH., Puthalakath, H., Rabinovich, GA., Rizzuto, R., Rodrigues, CM., Rubinsztein, DC., Rudel, T., Scorrano, L., Simon, HU., Steller, H., Tschopp, J., Tsujimoto, Y., Vandenabeele, P., Vitale, I., Vousden, KH., Youle, RJ., Yuan, J., Zhivotovsky, B., Kroemer, G. (2009). Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ. 16(8):1093-107 (abstract)
 
Gebeshuber, CA., Zatloukal, K., Martinez, J. (2009). miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. EMBO Rep. 10(4):400-5 (abstract)
 
Gruber, T., Hermann-Kleiter, N., Hinterleitner, R., Fresser, F., Schneider, R., Gastl, G., Penninger, JM., Baier, G. (2009). PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation. Sci Signal. 2(76):ra30 (abstract)
 
Guinea-Viniegra, J., Zenz, R., Scheuch, H., Hnisz, D., Holcmann, M., Bakiri, L., Schonthaler, HB., Sibilia, M., Wagner, EF. (2009). TNFalpha shedding and epidermal inflammation are controlled by Jun proteins. Genes Dev. 23(22):2663-74 (abstract)
 
Hanada, R., Leibbrandt, A., Hanada, T., Kitaoka, S., Furuyashiki, T., Fujihara, H., Trichereau, J., Paolino, M., Qadri, F., Plehm, R., Klaere, S., Komnenovic, V., Mimata, H., Yoshimatsu, H., Takahashi, N., von Haeseler, A., Bader, M., Kilic, SS., Ueta, Y., Pifl, C., Narumiya, S., Penninger, JM. (2009). Central control of fever and female body temperature by RANKL/RANK. Nature. 462(7272):505-9 (abstract)
 
Hayer, S., Pundt, N., Peters, MA., Wunrau, C., Kühnel, I., Neugebauer, K., Strietholt, S., Zwerina, J., Korb, A., Penninger, J., Joosten, LA., Gay, S., Rückle, T., Schett, G., Pap, T. (2009). PI3Kgamma regulates cartilage damage in chronic inflammatory arthritis. FASEB J. 23(12):4288-98 (abstract)
 
Hekimoglu, B., Ringrose, L. (2009). Non-coding RNAs in polycomb/trithorax regulation. RNA Biol. 6(2):129-37 (abstract)
 
Herzog, F., Primorac, I., Dube, P., Lenart, P., Sander, B., Mechtler, K., Stark, H., Peters, JM. (2009). Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science. 323(5920):1477-81 (abstract) (fulltext)
 
Holzmann, J., Pichler, P., Madalinski, M., Kurzbauer, R., Mechtler, K. (2009). Stoichiometry determination of the MP1-p14 complex using a novel and cost-efficient method to produce an equimolar mixture of standard peptides. Anal Chem. 81(24):10254-61 (abstract)
 
Joza, N., Pospisilik, JA., Hangen, E., Hanada, T., Modjtahedi, N., Penninger, JM., Kroemer, G. (2009). AIF: not just an apoptosis-inducing factor. Ann N Y Acad Sci. 1171:2-11 (abstract)
 
Karayel, E., Bürckstümmer, T., Bilban, M., Dürnberger, G., Weitzer, S., Martinez, J., Superti-Furga, G. (2009). The TLR-independent DNA recognition pathway in murine macrophages: Ligand features and molecular signature. Eur J Immunol. 39(7):1929-36 (abstract)
 
Kassiri, Z., Zhong, J., Guo, D., Basu, R., Wang, X., Liu, PP., Scholey, JW., Penninger, JM., Oudit, GY. (2009). Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction. Circ Heart Fail. 2(5):446-55 (abstract)
 
Kiermaier, E., Woehrer, S., Peng, Y., Mechtler, K., Westermann, S. (2009). A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast. Nat Cell Biol. 11(9):1109-15 (abstract)
 
Köcher, T., Pichler, P., Schutzbier, M., Stingl, C., Kaul, A., Teucher, N., Hasenfuss, G., Penninger, JM., Mechtler, K. (2009). High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all. J Proteome Res. 8(10):4743-52 (abstract)
 
Koestler, SA., Rottner, K., Lai, F., Block, J., Vinzenz, M., Small, JV. (2009). F- and G-actin concentrations in lamellipodia of moving cells. PLoS One. 4(3):e4810 (abstract)
 
Kurth, HM., Mochizuki, K. (2009). 2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena. RNA. 15(4):675-85 (abstract)
 
Kurth, HM., Mochizuki, K. (2009). Non-coding RNA: a bridge between small RNA and DNA. RNA Biol. 6(2):138-40 (abstract)
 
Lai, FP., Szczodrak, M., Oelkers, JM., Ladwein, M., Acconcia, F., Benesch, S., Auinger, S., Faix, J., Small, JV., Polo, S., Stradal, TE., Rottner, K. (2009). Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases. Mol Biol Cell. 20(14):3209-23 (abstract)
 
Leibbrandt, A., Penninger, JM. (2009). ESCI award lecture: from a little mouse to rationale medicine for bone loss. Eur J Clin Invest. 39(10):842-50 (abstract)
 
Leibbrandt, A., Penninger, JM. (2009). RANKL/RANK as key factors for osteoclast development and bone loss in arthropathies. Adv Exp Med Biol. 649:100-13 (abstract)
 
Leibbrandt, A., Penninger, JM. (2009). RANK(L) as a key target for controlling bone loss. Adv Exp Med Biol. 647:130-45 (abstract)
 
Leitner, A., Sturm, M., Smått, JH., Järn, M., Lindén, M., Mechtler, K., Lindner, W. (2009). Optimizing the performance of tin dioxide microspheres for phosphopeptide enrichment. Anal Chim Acta. 638(1):51-7 (abstract) (fulltext)
 
Loeser, S., Penninger, J.M. (2009). Regulation of T cell anergy and escape from regulatory T cells suppression by Cbl-b. In: The Epigenetics of Autoimmune disease. Ed. N. Zouali. :pp. 75-94
 
Loidl, J., Mochizuki, K. (2009). Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage. Mol Biol Cell. 20(9):2428-37 (abstract)
 
Mitulović, G., Stingl, C., Steinmacher, I., Hudecz, O., Hutchins, JR., Peters, JM., Mechtler, K. (2009). Preventing carryover of peptides and proteins in nano LC-MS separations. Anal Chem. 81(14):5955-60 (abstract)
 
Mizoguchi, T., Muto, A., Udagawa, N., Arai, A., Yamashita, T., Hosoya, A., Ninomiya, T., Nakamura, H., Yamamoto, Y., Kinugawa, S., Nakamura, M., Nakamichi, Y., Kobayashi, Y., Nagasawa, S., Oda, K., Tanaka, H., Tagaya, M., Penninger, JM., Ito, M., Takahashi, N. (2009). Identification of cell cycle-arrested quiescent osteoclast precursors in vivo. J Cell Biol. 184(4):541-54 (abstract)
 
Müller, MQ., de Koning, LJ., Schmidt, A., Ihling, C., Syha, Y., Rau, O., Mechtler, K., Schubert-Zsilavecz, M., Sinz, A. (2009). An innovative method to study target protein-drug interactions by mass spectrometry. J Med Chem. 52(9):2875-9 (abstract) (fulltext)
 
Mummery-Widmer, JL., Yamazaki, M., Stoeger, T., Novatchkova, M., Bhalerao, S., Chen, D., Dietzl, G., Dickson, BJ., Knoblich, JA. (2009). Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature. 458(7241):987-92 (abstract)
 
Nagatake, T., Fukuyama, S., Kim, DY., Goda, K., Igarashi, O., Sato, S., Nochi, T., Sagara, H., Yokota, Y., Jetten, AM., Kaisho, T., Akira, S., Mimuro, H., Sasakawa, C., Fukui, Y., Fujihashi, K., Akiyama, T., Inoue, J., Penninger, JM., Kunisawa, J., Kiyono, H. (2009). Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity. J Exp Med. 206(11):2351-64 (abstract)
 
Neumüller, RA., Knoblich, JA. (2009). Wicked views on stem cell news. Nat Cell Biol. 11(6):678-9 (abstract)
 
Neumüller, RA., Knoblich, JA. (2009). Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev. 23(23):2675-99 (abstract)
 
Nielsen, AF., Gloggnitzer, J., Martinez, J. (2009). Ars2 and the Cap-Binding Complex Team up for Silencing. Cell. 138(2):224-6 (abstract)
 
Nielsen, AF., Gloggnitzer, J., Martinez, J. (2009). MicroRNAs cross the line: the battle for mRNA stability enters the coding sequence. Mol Cell. 35(2):139-40 (abstract)
 
Ooi, HS., Kwo, CY., Wildpaner, M., Sirota, FL., Eisenhaber, B., Maurer-Stroh, S., Wong, WC., Schleiffer, A., Eisenhaber, F., Schneider, G. (2009). ANNIE: integrated de novo protein sequence annotation. Nucleic Acids Res. 37(Web Server issue):W435-40 (abstract)
 
Osterreicher, CH., Taura, K., De Minicis, S., Seki, E., Penz-Osterreicher, M., Kodama, Y., Kluwe, J., Schuster, M., Oudit, GY., Penninger, JM., Brenner, DA. (2009). Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. Hepatology. 50(3):929-38 (abstract)
 
Oudit, GY., Imai, Y., Kuba, K., Scholey, JW., Penninger, JM. (2009). The role of ACE2 in pulmonary diseases--relevance for the nephrologist. Nephrol Dial Transplant. 24(5):1362-5 (abstract)
 
Oudit, GY., Kassiri, Z., Jiang, C., Liu, PP., Poutanen, SM., Penninger, JM., Butany, J. (2009). SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS. Eur J Clin Invest. 39(7):618-25 (abstract)
 
Oudit, GY., Penninger, JM. (2009). Cardiac regulation by phosphoinositide 3-kinases and PTEN. Cardiovasc Res. 82(2):250-60 (abstract)
 
Paolino, M., Penninger, JM. (2009). E3 ubiquitin ligases in T-cell tolerance. Eur J Immunol. 39(9):2337-44 (abstract)
 
Penkner, AM., Fridkin, A., Gloggnitzer, J., Baudrimont, A., Machacek, T., Woglar, A., Csaszar, E., Pasierbek, P., Ammerer, G., Gruenbaum, Y., Jantsch, V. (2009). Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1. Cell. 139(5):920-33 (abstract)
 
Ringrose, L. (2009). Transgenesis in Drosophila melanogaster. Methods Mol Biol. 561:3-19 (abstract)
 
Rowland, BD., Roig, MB., Nishino, T., Kurze, A., Uluocak, P., Mishra, A., Beckouët, F., Underwood, P., Metson, J., Imre, R., Mechtler, K., Katis, VL., Nasmyth, K. (2009). Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell. 33(6):763-74 (abstract) (fulltext)
 
Schoft, VK., Chumak, N., Mosiolek, M., Slusarz, L., Komnenovic, V., Brownfield, L., Twell, D., Kakutani, T., Tamaru, H. (2009). Induction of RNA-directed DNA methylation upon decondensation of constitutive heterochromatin. EMBO Rep. 10(9):1015-21 (abstract)
 
Schwamborn, JC., Berezikov, E., Knoblich, JA. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell. 136(5):913-25 (abstract)
 
Siegel, G., Obernosterer, G., Fiore, R., Oehmen, M., Bicker, S., Christensen, M., Khudayberdiev, S., Leuschner, PF., Busch, CJ., Kane, C., Hübel, K., Dekker, F., Hedberg, C., Rengarajan, B., Drepper, C., Waldmann, H., Kauppinen, S., Greenberg, ME., Draguhn, A., Rehmsmeier, M., Martinez, J., Schratt, GM. (2009). A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol. 11(6):705-16 (abstract)
 
Singer, D., Camargo, SM., Huggel, K., Romeo, E., Danilczyk, U., Kuba, K., Chesnov, S., Caron, MG., Penninger, JM., Verrey, F. (2009). Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3. J Biol Chem. 284(30):19953-60 (abstract)
 
Spurrell, DR., Luckashenak, NA., Minney, DC., Chaplin, A., Penninger, JM., Liwski, RS., Clements, JL., West, KA. (2009). Vav1 regulates the migration and adhesion of dendritic cells. J Immunol. 183(1):310-8 (abstract)
 
Tanemura, S., Momose, H., Shimizu, N., Kitagawa, D., Seo, J., Yamasaki, T., Nakagawa, K., Kajiho, H., Penninger, JM., Katada, T., Nishina, H. (2009). Blockage by SP600125 of Fcepsilon receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signalling pathway. J Biochem. 145(3):345-54 (abstract)
 
Vallotton, P., Small, JV. (2009). Shifting views on the leading role of the lamellipodium in cell migration: speckle tracking revisited. J Cell Sci. 122(Pt 12):1955-8 (abstract) (fulltext)
 
Zhou, R., Czech, B., Brennecke, J., Sachidanandam, R., Wohlschlegel, JA., Perrimon, N., Hannon, GJ. (2009). Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA. 15(10):1886-95 (abstract)
 
Zimniak, T., Stengl, K., Mechtler, K., Westermann, S. (2009). Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p. J Cell Biol. 186(3):379-91 (abstract)
 

The Vienna Biocenter in the third district of Vienna has established itself as the premier location for life sciences in Central Europe and is a world-leading international bio-medical research center.

 

visit the Website