2008

Akiyama, T., Shimo, Y., Yanai, H., Qin, J., Ohshima, D., Maruyama, Y., Asaumi, Y., Kitazawa, J., Takayanagi, H., Penninger, JM., Matsumoto, M., Nitta, T., Takahama, Y., Inoue, J. (2008). The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity. 29(3):423-37 (abstract)
 
Aronica, L., Bednenko, J., Noto, T., DeSouza, LV., Siu, KW., Loidl, J., Pearlman, RE., Gorovsky, MA., Mochizuki, K. (2008). Study of an RNA helicase implicates small RNA-noncoding RNA interactions in programmed DNA elimination in Tetrahymena. Genes Dev. 22(16):2228-41 (abstract)
 
Auinger, S., Small, JV. (2008). Correlated light and electron microscopy of the cytoskeleton. Methods Cell Biol. 88:257-72 (abstract)
 
Ban, K., Cooper, AJ., Samuel, S., Bhatti, A., Patel, M., Izumo, S., Penninger, JM., Backx, PH., Oudit, GY., Tsushima, RG. (2008). Phosphatidylinositol 3-kinase gamma is a critical mediator of myocardial ischemic and adenosine-mediated preconditioning. Circ Res. 103(6):643-53 (abstract)
 
Barral, Y., Knoblich, J. (2008). Cell division, growth and death. Curr Opin Cell Biol. 20(6):647-9 (abstract)
 
Benetka, W., Mehlmer, N., Maurer-Stroh, S., Sammer, M., Koranda, M., Neumüller, R., Betschinger, J., Knoblich, JA., Teige, M., Eisenhaber, F. (2008). Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling. Cell Cycle. 7(23):3709-19 (abstract)
 
Block, J., Stradal, TE., Hänisch, J., Geffers, R., Köstler, SA., Urban, E., Small, JV., Rottner, K., Faix, J. (2008). Filopodia formation induced by active mDia2/Drf3. J Microsc. 231(3):506-17 (abstract)
 
Bortfeldt, R., Schindler, S., Szafranski, K., Schuster, S., Holste, D. (2008). Comparative analysis of sequence features involved in the recognition of tandem splice sites. BMC Genomics. 9:202 (abstract)
 
Bowman, SK., Rolland, V., Betschinger, J., Kinsey, KA., Emery, G., Knoblich, JA. (2008). The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Dev Cell. 14(4):535-46 (abstract)
 
Bozec, A., Bakiri, L., Hoebertz, A., Eferl, R., Schilling, AF., Komnenovic, V., Scheuch, H., Priemel, M., Stewart, CL., Amling, M., Wagner, EF. (2008). Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia. Nature. 454(7201):221-5 (abstract)
 
Breitsprecher, D., Kiesewetter, AK., Linkner, J., Urbanke, C., Resch, GP., Small, JV., Faix, J. (2008). Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation. EMBO J. 27(22):2943-54 (abstract)
 
Chavakis, E., Carmona, G., Urbich, C., Göttig, S., Henschler, R., Penninger, JM., Zeiher, AM., Chavakis, T., Dimmeler, S. (2008). Phosphatidylinositol-3-kinase-gamma is integral to homing functions of progenitor cells. Circ Res. 102(8):942-9 (abstract)
 
de la Fuente van Bentem, S., Anrather, D., Dohnal, I., Roitinger, E., Csaszar, E., Joore, J., Buijnink, J., Carreri, A., Forzani, C., Lorkovic, ZJ., Barta, A., Lecourieux, D., Verhounig, A., Jonak, C., Hirt, H. (2008). Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis. J Proteome Res. 7(6):2458-70 (abstract)
 
d'Erfurth, I., Jolivet, S., Froger, N., Catrice, O., Novatchkova, M., Simon, M., Jenczewski, E., Mercier, R. (2008). Mutations in AtPS1 (Arabidopsis thaliana parallel spindle 1) lead to the production of diploid pollen grains. PLoS Genet. 4(11):e1000274 (abstract)
 
Eferl, R., Hasselblatt, P., Rath, M., Popper, H., Zenz, R., Komnenovic, V., Idarraga, MH., Kenner, L., Wagner, EF. (2008). Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1. Proc Natl Acad Sci U S A. 105(30):10525-30 (abstract)
 
Efimov, A., Schiefermeier, N., Grigoriev, I., Ohi, R., Brown, MC., Turner, CE., Small, JV., Kaverina, I. (2008). Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites. J Cell Sci. 121(Pt 2):196-204 (abstract)
 
Galluzzi, L., Joza, N., Tasdemir, E., Maiuri, MC., Hengartner, M., Abrams, JM., Tavernarakis, N., Penninger, J., Madeo, F., Kroemer, G. (2008). No death without life: vital functions of apoptotic effectors. Cell Death Differ. 15(7):1113-23 (abstract)
 
Garabelli, PJ., Modrall, JG., Penninger, JM., Ferrario, CM., Chappell, MC. (2008). Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart. Exp Physiol. 93(5):613-21 (abstract)
 
Gebeshuber, C., Salvá Giró, A., Martinez, J. (2008). MicroRNAs and their impact on tumor initiation and progression. In: Human Epithelial Tumor Cell Plasticity: Implications for Cancer Progression and Metastasis. Ed. Paul J. Higgins. p:103
 
Hara, H., Ishihara, C., Takeuchi, A., Xue, L., Morris, SW., Penninger, JM., Yoshida, H., Saito, T. (2008). Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9. J Immunol. 181(2):918-30 (abstract)
 
Haubner, B. J., Neely, G., Pachinger, O., Penninger, J. M., Metzler, B. (2008). PI3Kgamma AKTing during myocardial ischemia and reperfusion. Wiener Klin. Wochenschrift. (15):95-97
 
Hauenschild, A., Ringrose, L., Altmutter, C., Paro, R., Rehmsmeier, M. (2008). Evolutionary plasticity of polycomb/trithorax response elements in Drosophila species. PLoS Biol. 6(10):e261 (abstract)
 
Hikosaka, Y., Nitta, T., Ohigashi, I., Yano, K., Ishimaru, N., Hayashi, Y., Matsumoto, M., Matsuo, K., Penninger, JM., Takayanagi, H., Yokota, Y., Yamada, H., Yoshikai, Y., Inoue, J., Akiyama, T., Takahama, Y. (2008). The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. Immunity. 29(3):438-50 (abstract)
 
Imai, Y., Kuba, K., Neely, GG., Yaghubian-Malhami, R., Perkmann, T., van Loo, G., Ermolaeva, M., Veldhuizen, R., Leung, YH., Wang, H., Liu, H., Sun, Y., Pasparakis, M., Kopf, M., Mech, C., Bavari, S., Peiris, JS., Slutsky, AS., Akira, S., Hultqvist, M., Holmdahl, R., Nicholls, J., Jiang, C., Binder, CJ., Penninger, JM. (2008). Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell. 133(2):235-49 (abstract)
 
Imai, Y., Kuba, K., Penninger, JM. (2008). The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice. Exp Physiol. 93(5):543-8 (abstract)
 
Imai, Y., Kuba, K., Penninger, JM. (2008). [Lessons from SARS: a new potential therapy for acute respiratory distress syndrome (ARDS) with angiotensin converting enzyme 2 (ACE2)]. Masui. 57(3):302-10 (abstract)
 
Joza, N., Galindo, K., Pospisilik, JA., Benit, P., Rangachari, M., Kanitz, EE., Nakashima, Y., Neely, GG., Rustin, P., Abrams, JM., Kroemer, G., Penninger, JM. (2008). The molecular archaeology of a mitochondrial death effector: AIF in Drosophila. Cell Death Differ. 15(6):1009-18 (abstract)
 
Jüschke, C., Knoblich, JA. (2008). Purification of Drosophila protein complexes for mass spectrometry. Methods Mol Biol. 420:347-58 (abstract)
 
Knoblich, JA. (2008). Mechanisms of asymmetric stem cell division. Cell. 132(4):583-97 (abstract)
 
Koestler, SA., Auinger, S., Vinzenz, M., Rottner, K., Small, JV. (2008). Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front. Nat Cell Biol. 10(3):306-13 (abstract)
 
Krojer, T., Pangerl, K., Kurt, J., Sawa, J., Stingl, C., Mechtler, K., Huber, R., Ehrmann, M., Clausen, T. (2008). Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins. Proc Natl Acad Sci U S A. 105(22):7702-7 (abstract)
 
Kuwana, H., Terada, Y., Kobayashi, T., Okado, T., Penninger, JM., Irie-Sasaki, J., Sasaki, T., Sasaki, S. (2008). The phosphoinositide-3 kinase gamma-Akt pathway mediates renal tubular injury in cisplatin nephrotoxicity. Kidney Int. 73(4):430-45 (abstract)
 
Lai, FP., Szczodrak, M., Block, J., Faix, J., Breitsprecher, D., Mannherz, HG., Stradal, TE., Dunn, GA., Small, JV., Rottner, K. (2008). Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J. 27(7):982-92 (abstract)
 
Leibbrandt, A., Penninger, J. M. (2008). RANK(L) as a key target for controlling bone loss. In: Therapeutic Targets of the TNF Superfamily. Ed. I. Grewal. Landes Bioscience/Eurekah.com.
 
Leibbrandt, A., Penninger, J. M. (2008). The role of RANKL in cancer. In: Encyclopedia of Cancer. Ed. Schwab, M. Springer.
 
Leibbrandt, A., Penninger, JM. (2008). RANK/RANKL: regulators of immune responses and bone physiology. Ann N Y Acad Sci. 1143:123-50 (abstract)
 
Lempradl, A., Ringrose, L. (2008). How does noncoding transcription regulate Hox genes? Bioessays. 30(2):110-21 (abstract)
 
Loeser, S., Penninger, J.M. (2008). The Role of the E3 ubiquitin ligase Cbl-b in T-cells signalling and tolerance. In: CBL Proteins. Ed. A. Tsygankov. Nova Science Publishers Inc. :Chapter 9
 
Lovren, F., Pan, Y., Quan, A., Teoh, H., Wang, G., Shukla, PC., Levitt, KS., Oudit, GY., Al-Omran, M., Stewart, DJ., Slutsky, AS., Peterson, MD., Backx, PH., Penninger, JM., Verma, S. (2008). Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis. Am J Physiol Heart Circ Physiol. 295(4):H1377-84 (abstract)
 
Macaisne, N., Novatchkova, M., Peirera, L., Vezon, D., Jolivet, S., Froger, N., Chelysheva, L., Grelon, M., Mercier, R. (2008). SHOC1, an XPF endonuclease-related protein, is essential for the formation of class I meiotic crossovers. Curr Biol. 18(18):1432-7 (abstract)
 
Martinez, J., Neugebauer, KM. (2008). El Sur también existe: processing RNA in the Argentine Patagonia. Meetings on 'Cell Biology, Signaling and Alternative Splicing' and 'Gene Expression and RNA Processing'. EMBO Rep. 9(6):516-20 (abstract)
 
Meixner, A., Zenz, R., Schonthaler, HB., Kenner, L., Scheuch, H., Penninger, JM., Wagner, EF. (2008). Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation. Nat Cell Biol. 10(8):1003-11 (abstract)
 
Mochizuki, K. (2008). High efficiency transformation of Tetrahymena using a codon-optimized neomycin resistance gene. Gene. 425(1-2):79-83 (abstract)
 
Mochizuki, K., Novatchkova, M., Loidl, J. (2008). DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena. J Cell Sci. 121(Pt 13):2148-58 (abstract)
 
Nemethova, M., Auinger, S., Small, JV. (2008). Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella. J Cell Biol. 180(6):1233-44 (abstract)
 
Neumüller, RA., Betschinger, J., Fischer, A., Bushati, N., Poernbacher, I., Mechtler, K., Cohen, SM., Knoblich, JA. (2008). Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature. 454(7201):241-5 (abstract)
 
Obernosterer, G., Tafer, H., Martinez, J. (2008). Target site effects in the RNA interference and microRNA pathways. Biochem Soc Trans. 36(Pt 6):1216-9 (abstract)
 
Oelz, D., Schmeiser, C., Small, JV. (2008). Modeling of the actin-cytoskeleton in symmetric lamellipodial fragments. Cell Adh Migr. 2(2):117-26 (abstract)
 
Oudit, GY., Kassiri, Z., Zhou, J., Liu, QC., Liu, PP., Backx, PH., Dawood, F., Crackower, MA., Scholey, JW., Penninger, JM. (2008). Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress. Cardiovasc Res. 78(3):505-14 (abstract)
 
Penninger, J., Imai, Y., Kuba, K. (2008). The discovery of ACE2 and its role in acute lung injury. Exp Physiol. (abstract)
 
Penninger, J.M. (2008). Do genes dream? In: Identitaet(en). Ed. GLOBArt. Springer.
 
Poser, I., Sarov, M., Hutchins, JR., Hériché, JK., Toyoda, Y., Pozniakovsky, A., Weigl, D., Nitzsche, A., Hegemann, B., Bird, AW., Pelletier, L., Kittler, R., Hua, S., Naumann, R., Augsburg, M., Sykora, MM., Hofemeister, H., Zhang, Y., Nasmyth, K., White, KP., Dietzel, S., Mechtler, K., Durbin, R., Stewart, AF., Peters, JM., Buchholz, F., Hyman, AA. (2008). BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods. 5(5):409-15 (abstract)
 
Qiao, G., Li, Z., Molinero, L., Alegre, ML., Ying, H., Sun, Z., Penninger, JM., Zhang, J. (2008). T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b. Mol Cell Biol. 28(7):2470-80 (abstract)
 
Raberger, J., Boucheron, N., Sakaguchi, S., Penninger, JM., Ellmeier, W. (2008). Impaired T-cell development in the absence of Vav1 and Itk. Eur J Immunol. 38(12):3530-42 (abstract)
 
Reich, HN., Oudit, GY., Penninger, JM., Scholey, JW., Herzenberg, AM. (2008). Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease. Kidney Int. 74(12):1610-6 (abstract)
 
Riehs, N., Akimcheva, S., Puizina, J., Bulankova, P., Idol, RA., Siroky, J., Schleiffer, A., Schweizer, D., Shippen, DE., Riha, K. (2008). Arabidopsis SMG7 protein is required for exit from meiosis. J Cell Sci. 121(Pt 13):2208-16 (abstract)
 
Schmidt, A., Csaszar, E., Ammerer, G., Mechtler, K. (2008). Enhanced detection and identification of multiply phosphorylated peptides using TiO2 enrichment in combination with MALDI TOF/TOF MS. Proteomics. 8(21):4577-92 (abstract)
 
Schwamborn, JC., Knoblich, JA. (2008). LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell. 2(3):193-4 (abstract)
 
Scott, RS., Li, Z., Paulin, D., Uvelius, B., Small, JV., Arner, A. (2008). Role of desmin in active force transmission and maintenance of structure during growth of urinary bladder. Am J Physiol Cell Physiol. 295(2):C324-31 (abstract)
 
Small, JV. (2008). Facing up to Mena: Tes(ting) times for EVH1 domains. Nat Cell Biol. 10(2):118-20 (abstract)
 
Small, JV., Auinger, S., Nemethova, M., Koestler, S., Goldie, KN., Hoenger, A., Resch, GP. (2008). Unravelling the structure of the lamellipodium. J Microsc. 231(3):479-85 (abstract)
 
Speicher, S., Fischer, A., Knoblich, J., Carmena, A. (2008). The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors. Curr Biol. 18(11):831-7 (abstract)
 
Tafer, H., Ameres, SL., Obernosterer, G., Gebeshuber, CA., Schroeder, R., Martinez, J., Hofacker, IL. (2008). The impact of target site accessibility on the design of effective siRNAs. Nat Biotechnol. 26(5):578-83 (abstract)
 
Tomasi, T., Hakeda-Suzuki, S., Ohler, S., Schleiffer, A., Suzuki, T. (2008). The transmembrane protein Golden goal regulates R8 photoreceptor axon-axon and axon-target interactions. Neuron. 57(5):691-704 (abstract)
 
Wada, T., Stepniak, E., Hui, L., Leibbrandt, A., Katada, T., Nishina, H., Wagner, EF., Penninger, JM. (2008). Antagonistic control of cell fates by JNK and p38-MAPK signaling. Cell Death Differ. 15(1):89-93 (abstract)
 
Winter, S., Simboeck, E., Fischle, W., Zupkovitz, G., Dohnal, I., Mechtler, K., Ammerer, G., Seiser, C. (2008). 14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation. EMBO J. 27(1):88-99 (abstract)
 
Wirtz-Peitz, F., Nishimura, T., Knoblich, JA. (2008). Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell. 135(1):161-73 (abstract)
 
Yotova, IY., Vlatkovic, IM., Pauler, FM., Warczok, KE., Ambros, PF., Oshimura, M., Theussl, HC., Gessler, M., Wagner, EF., Barlow, DP. (2008). Identification of the human homolog of the imprinted mouse Air non-coding RNA. Genomics. 92(6):464-73 (abstract)
 

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