Alnaeeli, M., Park, J., Mahamed, D., Penninger, JM., Teng, YT. (2007). Dendritic cells at the osteo-immune interface: implications for inflammation-induced bone loss.
J Bone Miner Res. 22(6):775-80
(abstract)
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Ameres, SL., Martinez, J., Schroeder, R. (2007). Molecular basis for target RNA recognition and cleavage by human RISC.
Cell. 130(1):101-12
(abstract)
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Andrade, N., Komnenovic, V., Blake, SM., Jossin, Y., Howell, B., Goffinet, A., Schneider, WJ., Nimpf, J. (2007). ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin.
Proc Natl Acad Sci U S A. 104(20):8508-13
(abstract)
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Bakiri, L., Takada, Y., Radolf, M., Eferl, R., Yaniv, M., Wagner, EF., Matsuo, K. (2007). Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation.
Bone. 40(4):867-75
(abstract)
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Burkard, T. R., Trajanoski, Z., Novatchkova, M., Hackl, H., Eisenhaber, F. (2007). Identification of new targets using expression profiling.
In Antiangiogenic cancer therapy (Davis, D.R., Herbst, R.S., & Abbruzzese, J.L., eds.); CRC Press Taylor & Francis Group, Boca Raton London New York.. :415-41
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Cronin, SJ., Penninger, JM. (2007). From T-cell activation signals to signaling control of anti-cancer immunity.
Immunol Rev. 220:151-68
(abstract)
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Dietzl, G., Chen, D., Schnorrer, F., Su, KC., Barinova, Y., Fellner, M., Gasser, B., Kinsey, K., Oppel, S., Scheiblauer, S., Couto, A., Marra, V., Keleman, K., Dickson, BJ. (2007). A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila.
Nature. 448(7150):151-6
(abstract)
(fulltext)
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Eferl, R., Zenz, R., Theussl, HC., Wagner, EF. (2007). Simultaneous generation of fra-2 conditional and fra-2 knock-out mice.
Genesis. 45(7):447-51
(abstract)
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Efimov, A., Kharitonov, A., Efimova, N., Loncarek, J., Miller, PM., Andreyeva, N., Gleeson, P., Galjart, N., Maia, AR., McLeod, IX., Yates, JR., Maiato, H., Khodjakov, A., Akhmanova, A., Kaverina, I. (2007). Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network.
Dev Cell. 12(6):917-30
(abstract)
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Feraud, O., Debili, N., Penninger, JM., Kroemer, G. (2007). Cavitation of embryoid bodies requires optimal oxidative phosphorylation and AIF.
Cell Death Differ. 14(2):385-7
(abstract)
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Fischer, L., Gukovskaya, AS., Penninger, JM., Mareninova, OA., Friess, H., Gukovsky, I., Pandol, SJ. (2007). Phosphatidylinositol 3-kinase facilitates bile acid-induced Ca(2+) responses in pancreatic acinar cells.
Am J Physiol Gastrointest Liver Physiol. 292(3):G875-86
(abstract)
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Gillardon, F., Kloss, A., Berg, M., Neumann, M., Mechtler, K., Hengerer, B., Dahlmann, B. (2007). The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity.
J Neurochem. 101(6):1483-90
(abstract)
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Gregan, J., Riedel, CG., Petronczki, M., Cipak, L., Rumpf, C., Poser, I., Buchholz, F., Mechtler, K., Nasmyth, K. (2007). Tandem affinity purification of functional TAP-tagged proteins from human cells.
Nat Protoc. 2(5):1145-51
(abstract)
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Gregan, J., Riedel, CG., Pidoux, AL., Katou, Y., Rumpf, C., Schleiffer, A., Kearsey, SE., Shirahige, K., Allshire, RC., Nasmyth, K. (2007). The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation.
Curr Biol. 17(14):1190-200
(abstract)
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Hara, H., Ishihara, C., Takeuchi, A., Imanishi, T., Xue, L., Morris, SW., Inui, M., Takai, T., Shibuya, A., Saijo, S., Iwakura, Y., Ohno, N., Koseki, H., Yoshida, H., Penninger, JM., Saito, T. (2007). The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors.
Nat Immunol. 8(6):619-29
(abstract)
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Hartler, J., Thallinger, GG., Stocker, G., Sturn, A., Burkard, TR., Körner, E., Rader, R., Schmidt, A., Mechtler, K., Trajanoski, Z. (2007). MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data.
BMC Bioinformatics. 8:197
(abstract)
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Hasselblatt, P., Rath, M., Komnenovic, V., Zatloukal, K., Wagner, EF. (2007). Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase.
Proc Natl Acad Sci U S A. 104(43):17105-10
(abstract)
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Hui, L., Bakiri, L., Mairhorfer, A., Schweifer, N., Haslinger, C., Kenner, L., Komnenovic, V., Scheuch, H., Beug, H., Wagner, EF. (2007). p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway.
Nat Genet. 39(6):741-9
(abstract)
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Imai, Y., Kuba, K., Penninger, JM. (2007). Angiotensin-converting enzyme 2 in acute respiratory distress syndrome.
Cell Mol Life Sci. 64(15):2006-12
(abstract)
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Jantsch, V., Tang, L., Pasierbek, P., Penkner, A., Nayak, S., Baudrimont, A., Schedl, T., Gartner, A., Loidl, J. (2007). Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing.
Mol Biol Cell. 18(12):4911-20
(abstract)
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Keleman, K., Krüttner, S., Alenius, M., Dickson, BJ. (2007). Function of the Drosophila CPEB protein Orb2 in long-term courtship memory.
Nat Neurosci. 10(12):1587-93
(abstract)
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Knoblich, J. (2007). On the backroads to cellular asymmetry.
Development (Cambridge, England). 134(24):4311-3
(abstract)
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Kuba, K., Zhang, L., Imai, Y., Arab, S., Chen, M., Maekawa, Y., Leschnik, M., Leibbrandt, A., Markovic, M., Makovic, M., Schwaighofer, J., Beetz, N., Musialek, R., Neely, GG., Komnenovic, V., Kolm, U., Metzler, B., Ricci, R., Hara, H., Meixner, A., Nghiem, M., Chen, X., Dawood, F., Wong, KM., Sarao, R., Cukerman, E., Kimura, A., Hein, L., Thalhammer, J., Liu, PP., Penninger, JM. (2007). Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.
Circ Res. 101(4):e32-42
(abstract)
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Kubicek, S., O'Sullivan, RJ., August, EM., Hickey, ER., Zhang, Q., Teodoro, ML., Rea, S., Mechtler, K., Kowalski, JA., Homon, CA., Kelly, TA., Jenuwein, T. (2007). Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Mol Cell. 25(3):473-81
(abstract)
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Leuschner, PJ., Martinez, J. (2007). In vitro analysis of microRNA processing using recombinant Dicer and cytoplasmic extracts of HeLa cells.
Methods. 43(2):105-9
(abstract)
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Liu, L., Puri, KD., Penninger, JM., Kubes, P. (2007). Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo.
Blood. 110(4):1191-8
(abstract)
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Loeser, S., Loser, K., Bijker, MS., Rangachari, M., van der Burg, SH., Wada, T., Beissert, S., Melief, CJ., Penninger, JM. (2007). Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells.
J Exp Med. 204(4):879-91
(abstract)
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Loeser, S., Penninger, JM. (2007). Regulation of peripheral T cell tolerance by the E3 ubiquitin ligase Cbl-b.
Semin Immunol. 19(3):206-14
(abstract)
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Loeser, S., Penninger, JM. (2007). The ubiquitin E3 ligase Cbl-b in T cells tolerance and tumor immunity.
Cell Cycle. 6(20):2478-85
(abstract)
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Martinez, J., Busslinger, M. (2007). Life beyond cleavage: the case of Ago2 and hematopoiesis.
Genes Dev. 21(16):1983-8
(abstract)
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Mazanek, M., Mituloviae, G., Herzog, F., Stingl, C., Hutchins, JR., Peters, JM., Mechtler, K. (2007). Titanium dioxide as a chemo-affinity solid phase in offline phosphopeptide chromatography prior to HPLC-MS/MS analysis.
Nat Protoc. 2(5):1059-69
(abstract)
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Nakamichi, Y., Udagawa, N., Kobayashi, Y., Nakamura, M., Yamamoto, Y., Yamashita, T., Mizoguchi, T., Sato, M., Mogi, M., Penninger, JM., Takahashi, N. (2007). Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand derived from osteoblasts.
J Immunol. 178(1):192-200
(abstract)
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Nielsen, AF., Leuschner, PJ., Martinez, J. (2007). Not miR-ly a splicing factor: hnRNP A1 succumbs to microRNA temptation.
Nat Struct Mol Biol. 14(7):572-3
(abstract)
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Nishio, M., Watanabe, K., Sasaki, J., Taya, C., Takasuga, S., Iizuka, R., Balla, T., Yamazaki, M., Watanabe, H., Itoh, R., Kuroda, S., Horie, Y., Förster, I., Mak, TW., Yonekawa, H., Penninger, JM., Kanaho, Y., Suzuki, A., Sasaki, T. (2007). Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1.
Nat Cell Biol. 9(1):36-44
(abstract)
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Obernosterer, G., Martinez, J., Alenius, M. (2007). Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections.
Nat Protoc. 2(6):1508-14
(abstract)
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Obernosterer, G., Meister, G., Poy, MN., Kuras, A. (2007). The impact of small RNAs. Microsymposium on small RNAs.
EMBO Rep. 8(1):23-7
(abstract)
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Oudit, GY., Kassiri, Z., Patel, MP., Chappell, M., Butany, J., Backx, PH., Tsushima, RG., Scholey, JW., Khokha, R., Penninger, JM. (2007). Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
Cardiovasc Res. 75(1):29-39
(abstract)
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Pasquali, C., Bertschy-Meier, D., Chabert, C., Curchod, ML., Arod, C., Booth, R., Mechtler, K., Vilbois, F., Xenarios, I., Ferguson, CG., Prestwich, GD., Camps, M., Rommel, C. (2007). A chemical proteomics approach to phosphatidylinositol 3-kinase signaling in macrophages.
Mol Cell Proteomics. 6(11):1829-41
(abstract)
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Penkner, A., Portik-Dobos, Z., Tang, L., Schnabel, R., Novatchkova, M., Jantsch, V., Loidl, J. (2007). A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination.
EMBO J. 26(24):5071-82
(abstract)
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Penkner, A., Tang, L., Novatchkova, M., Ladurner, M., Fridkin, A., Gruenbaum, Y., Schweizer, D., Loidl, J., Jantsch, V. (2007). The nuclear envelope protein Matefin/SUN-1 is required for homologous pairing in C. elegans meiosis.
Dev Cell. 12(6):873-85
(abstract)
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Pospisilik, JA., Knauf, C., Joza, N., Benit, P., Orthofer, M., Cani, PD., Ebersberger, I., Nakashima, T., Sarao, R., Neely, G., Esterbauer, H., Kozlov, A., Kahn, CR., Kroemer, G., Rustin, P., Burcelin, R., Penninger, JM. (2007). Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.
Cell. 131(3):476-91
(abstract)
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Regha, K., Sloane, MA., Huang, R., Pauler, FM., Warczok, KE., Melikant, B., Radolf, M., Martens, JH., Schotta, G., Jenuwein, T., Barlow, DP. (2007). Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.
Mol Cell. 27(3):353-66
(abstract)
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Ringrose, L. (2007). Polycomb comes of age: genome-wide profiling of target sites.
Curr Opin Cell Biol. 19(3):290-7
(abstract)
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Ringrose, L., Paro, R. (2007). Polycomb/Trithorax response elements and epigenetic memory of cell identity.
Development. 134(2):223-32
(abstract)
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Rossi, SW., Kim, MY., Leibbrandt, A., Parnell, SM., Jenkinson, WE., Glanville, SH., McConnell, FM., Scott, HS., Penninger, JM., Jenkinson, EJ., Lane, PJ., Anderson, G. (2007). RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla.
J Exp Med. 204(6):1267-72
(abstract)
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Schittenhelm, RB., Heeger, S., Althoff, F., Walter, A., Heidmann, S., Mechtler, K., Lehner, CF. (2007). Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes.
Chromosoma. 116(4):385-402
(abstract)
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Schmitz, J., Watrin, E., Lénárt, P., Mechtler, K., Peters, JM. (2007). Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.
Curr Biol. 17(7):630-6
(abstract)
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Schulz, DM., Kalkhof, S., Schmidt, A., Ihling, C., Stingl, C., Mechtler, K., Zschörnig, O., Sinz, A. (2007). Annexin A2/P11 interaction: new insights into annexin A2 tetramer structure by chemical crosslinking, high-resolution mass spectrometry, and computational modeling.
Proteins. 69(2):254-69
(abstract)
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Séverin, S., Gratacap, MP., Lenain, N., Alvarez, L., Hollande, E., Penninger, JM., Gachet, C., Plantavid, M., Payrastre, B. (2007). Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth.
J Clin Invest. 117(4):944-52
(abstract)
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Shambharkar, PB., Blonska, M., Pappu, BP., Li, H., You, Y., Sakurai, H., Darnay, BG., Hara, H., Penninger, J., Lin, X. (2007). Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways.
EMBO J. 26(7):1794-805
(abstract)
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Skok, JA., Gisler, R., Novatchkova, M., Farmer, D., de Laat, W., Busslinger, M. (2007). Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes.
Nat Immunol. 8(4):378-87
(abstract)
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Tassi, I., Cella, M., Gilfillan, S., Turnbull, I., Diacovo, TG., Penninger, JM., Colonna, M. (2007). p110gamma and p110delta phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells.
Immunity. 27(2):214-27
(abstract)
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Uanschou, C., Siwiec, T., Pedrosa-Harand, A., Kerzendorfer, C., Sanchez-Moran, E., Novatchkova, M., Akimcheva, S., Woglar, A., Klein, F., Schlögelhofer, P. (2007). A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene.
EMBO J. 26(24):5061-70
(abstract)
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Weitzer, S., Martinez, J. (2007). hClp1: a novel kinase revitalizes RNA metabolism.
Cell Cycle. 6(17):2133-7
(abstract)
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Weitzer, S., Martinez, J. (2007). The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs.
Nature. 447(7141):222-6
(abstract)
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Wiesenberger, G., Speer, F., Haller, G., Bonnefoy, N., Schleiffer, A., Schafer, B. (2007). RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes.
J Mol Biol. 367(3):681-91
(abstract)
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Wong, DW., Oudit, GY., Reich, H., Kassiri, Z., Zhou, J., Liu, QC., Backx, PH., Penninger, JM., Herzenberg, AM., Scholey, JW. (2007). Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury.
Am J Pathol. 171(2):438-51
(abstract)
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Zhang, L., Anglesio, MS., O'Sullivan, M., Zhang, F., Yang, G., Sarao, R., Mai, PN., Cronin, S., Hara, H., Melnyk, N., Li, L., Wada, T., Liu, PP., Farrar, J., Arceci, RJ., Sorensen, PH., Penninger, JM. (2007). The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.
Nat Med. 13(9):1060-9
(abstract)
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Zuber, AM., Singer, D., Penninger, JM., Rossier, BC., Firsov, D. (2007). Increased renal responsiveness to vasopressin and enhanced V2 receptor signaling in RGS2-/- mice.
J Am Soc Nephrol. 18(6):1672-8
(abstract)
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