2007

Alnaeeli, M., Park, J., Mahamed, D., Penninger, JM., Teng, YT. (2007). Dendritic cells at the osteo-immune interface: implications for inflammation-induced bone loss. J Bone Miner Res. 22(6):775-80 (abstract)
 
Ameres, SL., Martinez, J., Schroeder, R. (2007). Molecular basis for target RNA recognition and cleavage by human RISC. Cell. 130(1):101-12 (abstract)
 
Andrade, N., Komnenovic, V., Blake, SM., Jossin, Y., Howell, B., Goffinet, A., Schneider, WJ., Nimpf, J. (2007). ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin. Proc Natl Acad Sci U S A. 104(20):8508-13 (abstract)
 
Bakiri, L., Takada, Y., Radolf, M., Eferl, R., Yaniv, M., Wagner, EF., Matsuo, K. (2007). Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation. Bone. 40(4):867-75 (abstract)
 
Burkard, T. R., Trajanoski, Z., Novatchkova, M., Hackl, H., Eisenhaber, F. (2007). Identification of new targets using expression profiling. In Antiangiogenic cancer therapy (Davis, D.R., Herbst, R.S., & Abbruzzese, J.L., eds.); CRC Press Taylor & Francis Group, Boca Raton London New York.. :415-41
 
Cronin, SJ., Penninger, JM. (2007). From T-cell activation signals to signaling control of anti-cancer immunity. Immunol Rev. 220:151-68 (abstract)
 
Dietzl, G., Chen, D., Schnorrer, F., Su, KC., Barinova, Y., Fellner, M., Gasser, B., Kinsey, K., Oppel, S., Scheiblauer, S., Couto, A., Marra, V., Keleman, K., Dickson, BJ. (2007). A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature. 448(7150):151-6 (abstract) (fulltext)
 
Eferl, R., Zenz, R., Theussl, HC., Wagner, EF. (2007). Simultaneous generation of fra-2 conditional and fra-2 knock-out mice. Genesis. 45(7):447-51 (abstract)
 
Efimov, A., Kharitonov, A., Efimova, N., Loncarek, J., Miller, PM., Andreyeva, N., Gleeson, P., Galjart, N., Maia, AR., McLeod, IX., Yates, JR., Maiato, H., Khodjakov, A., Akhmanova, A., Kaverina, I. (2007). Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network. Dev Cell. 12(6):917-30 (abstract)
 
Feraud, O., Debili, N., Penninger, JM., Kroemer, G. (2007). Cavitation of embryoid bodies requires optimal oxidative phosphorylation and AIF. Cell Death Differ. 14(2):385-7 (abstract)
 
Fischer, L., Gukovskaya, AS., Penninger, JM., Mareninova, OA., Friess, H., Gukovsky, I., Pandol, SJ. (2007). Phosphatidylinositol 3-kinase facilitates bile acid-induced Ca(2+) responses in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 292(3):G875-86 (abstract)
 
Gillardon, F., Kloss, A., Berg, M., Neumann, M., Mechtler, K., Hengerer, B., Dahlmann, B. (2007). The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity. J Neurochem. 101(6):1483-90 (abstract)
 
Gregan, J., Riedel, CG., Petronczki, M., Cipak, L., Rumpf, C., Poser, I., Buchholz, F., Mechtler, K., Nasmyth, K. (2007). Tandem affinity purification of functional TAP-tagged proteins from human cells. Nat Protoc. 2(5):1145-51 (abstract)
 
Gregan, J., Riedel, CG., Pidoux, AL., Katou, Y., Rumpf, C., Schleiffer, A., Kearsey, SE., Shirahige, K., Allshire, RC., Nasmyth, K. (2007). The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation. Curr Biol. 17(14):1190-200 (abstract)
 
Hara, H., Ishihara, C., Takeuchi, A., Imanishi, T., Xue, L., Morris, SW., Inui, M., Takai, T., Shibuya, A., Saijo, S., Iwakura, Y., Ohno, N., Koseki, H., Yoshida, H., Penninger, JM., Saito, T. (2007). The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors. Nat Immunol. 8(6):619-29 (abstract)
 
Hartler, J., Thallinger, GG., Stocker, G., Sturn, A., Burkard, TR., Körner, E., Rader, R., Schmidt, A., Mechtler, K., Trajanoski, Z. (2007). MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data. BMC Bioinformatics. 8:197 (abstract)
 
Hasselblatt, P., Rath, M., Komnenovic, V., Zatloukal, K., Wagner, EF. (2007). Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase. Proc Natl Acad Sci U S A. 104(43):17105-10 (abstract)
 
Hui, L., Bakiri, L., Mairhorfer, A., Schweifer, N., Haslinger, C., Kenner, L., Komnenovic, V., Scheuch, H., Beug, H., Wagner, EF. (2007). p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nat Genet. 39(6):741-9 (abstract)
 
Imai, Y., Kuba, K., Penninger, JM. (2007). Angiotensin-converting enzyme 2 in acute respiratory distress syndrome. Cell Mol Life Sci. 64(15):2006-12 (abstract)
 
Jantsch, V., Tang, L., Pasierbek, P., Penkner, A., Nayak, S., Baudrimont, A., Schedl, T., Gartner, A., Loidl, J. (2007). Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing. Mol Biol Cell. 18(12):4911-20 (abstract)
 
Keleman, K., Krüttner, S., Alenius, M., Dickson, BJ. (2007). Function of the Drosophila CPEB protein Orb2 in long-term courtship memory. Nat Neurosci. 10(12):1587-93 (abstract)
 
Knoblich, J. (2007). On the backroads to cellular asymmetry. Development (Cambridge, England). 134(24):4311-3 (abstract)
 
Kuba, K., Zhang, L., Imai, Y., Arab, S., Chen, M., Maekawa, Y., Leschnik, M., Leibbrandt, A., Markovic, M., Makovic, M., Schwaighofer, J., Beetz, N., Musialek, R., Neely, GG., Komnenovic, V., Kolm, U., Metzler, B., Ricci, R., Hara, H., Meixner, A., Nghiem, M., Chen, X., Dawood, F., Wong, KM., Sarao, R., Cukerman, E., Kimura, A., Hein, L., Thalhammer, J., Liu, PP., Penninger, JM. (2007). Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res. 101(4):e32-42 (abstract)
 
Kubicek, S., O'Sullivan, RJ., August, EM., Hickey, ER., Zhang, Q., Teodoro, ML., Rea, S., Mechtler, K., Kowalski, JA., Homon, CA., Kelly, TA., Jenuwein, T. (2007). Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell. 25(3):473-81 (abstract)
 
Leuschner, PJ., Martinez, J. (2007). In vitro analysis of microRNA processing using recombinant Dicer and cytoplasmic extracts of HeLa cells. Methods. 43(2):105-9 (abstract)
 
Liu, L., Puri, KD., Penninger, JM., Kubes, P. (2007). Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo. Blood. 110(4):1191-8 (abstract)
 
Loeser, S., Loser, K., Bijker, MS., Rangachari, M., van der Burg, SH., Wada, T., Beissert, S., Melief, CJ., Penninger, JM. (2007). Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells. J Exp Med. 204(4):879-91 (abstract)
 
Loeser, S., Penninger, JM. (2007). Regulation of peripheral T cell tolerance by the E3 ubiquitin ligase Cbl-b. Semin Immunol. 19(3):206-14 (abstract)
 
Loeser, S., Penninger, JM. (2007). The ubiquitin E3 ligase Cbl-b in T cells tolerance and tumor immunity. Cell Cycle. 6(20):2478-85 (abstract)
 
Martinez, J., Busslinger, M. (2007). Life beyond cleavage: the case of Ago2 and hematopoiesis. Genes Dev. 21(16):1983-8 (abstract)
 
Mazanek, M., Mituloviae, G., Herzog, F., Stingl, C., Hutchins, JR., Peters, JM., Mechtler, K. (2007). Titanium dioxide as a chemo-affinity solid phase in offline phosphopeptide chromatography prior to HPLC-MS/MS analysis. Nat Protoc. 2(5):1059-69 (abstract)
 
Nakamichi, Y., Udagawa, N., Kobayashi, Y., Nakamura, M., Yamamoto, Y., Yamashita, T., Mizoguchi, T., Sato, M., Mogi, M., Penninger, JM., Takahashi, N. (2007). Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand derived from osteoblasts. J Immunol. 178(1):192-200 (abstract)
 
Nielsen, AF., Leuschner, PJ., Martinez, J. (2007). Not miR-ly a splicing factor: hnRNP A1 succumbs to microRNA temptation. Nat Struct Mol Biol. 14(7):572-3 (abstract)
 
Nishio, M., Watanabe, K., Sasaki, J., Taya, C., Takasuga, S., Iizuka, R., Balla, T., Yamazaki, M., Watanabe, H., Itoh, R., Kuroda, S., Horie, Y., Förster, I., Mak, TW., Yonekawa, H., Penninger, JM., Kanaho, Y., Suzuki, A., Sasaki, T. (2007). Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat Cell Biol. 9(1):36-44 (abstract)
 
Obernosterer, G., Martinez, J., Alenius, M. (2007). Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat Protoc. 2(6):1508-14 (abstract)
 
Obernosterer, G., Meister, G., Poy, MN., Kuras, A. (2007). The impact of small RNAs. Microsymposium on small RNAs. EMBO Rep. 8(1):23-7 (abstract)
 
Oudit, GY., Kassiri, Z., Patel, MP., Chappell, M., Butany, J., Backx, PH., Tsushima, RG., Scholey, JW., Khokha, R., Penninger, JM. (2007). Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc Res. 75(1):29-39 (abstract)
 
Pasquali, C., Bertschy-Meier, D., Chabert, C., Curchod, ML., Arod, C., Booth, R., Mechtler, K., Vilbois, F., Xenarios, I., Ferguson, CG., Prestwich, GD., Camps, M., Rommel, C. (2007). A chemical proteomics approach to phosphatidylinositol 3-kinase signaling in macrophages. Mol Cell Proteomics. 6(11):1829-41 (abstract)
 
Penkner, A., Portik-Dobos, Z., Tang, L., Schnabel, R., Novatchkova, M., Jantsch, V., Loidl, J. (2007). A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination. EMBO J. 26(24):5071-82 (abstract)
 
Penkner, A., Tang, L., Novatchkova, M., Ladurner, M., Fridkin, A., Gruenbaum, Y., Schweizer, D., Loidl, J., Jantsch, V. (2007). The nuclear envelope protein Matefin/SUN-1 is required for homologous pairing in C. elegans meiosis. Dev Cell. 12(6):873-85 (abstract)
 
Pospisilik, JA., Knauf, C., Joza, N., Benit, P., Orthofer, M., Cani, PD., Ebersberger, I., Nakashima, T., Sarao, R., Neely, G., Esterbauer, H., Kozlov, A., Kahn, CR., Kroemer, G., Rustin, P., Burcelin, R., Penninger, JM. (2007). Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell. 131(3):476-91 (abstract)
 
Regha, K., Sloane, MA., Huang, R., Pauler, FM., Warczok, KE., Melikant, B., Radolf, M., Martens, JH., Schotta, G., Jenuwein, T., Barlow, DP. (2007). Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome. Mol Cell. 27(3):353-66 (abstract)
 
Ringrose, L. (2007). Polycomb comes of age: genome-wide profiling of target sites. Curr Opin Cell Biol. 19(3):290-7 (abstract)
 
Ringrose, L., Paro, R. (2007). Polycomb/Trithorax response elements and epigenetic memory of cell identity. Development. 134(2):223-32 (abstract)
 
Rossi, SW., Kim, MY., Leibbrandt, A., Parnell, SM., Jenkinson, WE., Glanville, SH., McConnell, FM., Scott, HS., Penninger, JM., Jenkinson, EJ., Lane, PJ., Anderson, G. (2007). RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J Exp Med. 204(6):1267-72 (abstract)
 
Schittenhelm, RB., Heeger, S., Althoff, F., Walter, A., Heidmann, S., Mechtler, K., Lehner, CF. (2007). Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes. Chromosoma. 116(4):385-402 (abstract)
 
Schmitz, J., Watrin, E., Lénárt, P., Mechtler, K., Peters, JM. (2007). Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase. Curr Biol. 17(7):630-6 (abstract)
 
Schulz, DM., Kalkhof, S., Schmidt, A., Ihling, C., Stingl, C., Mechtler, K., Zschörnig, O., Sinz, A. (2007). Annexin A2/P11 interaction: new insights into annexin A2 tetramer structure by chemical crosslinking, high-resolution mass spectrometry, and computational modeling. Proteins. 69(2):254-69 (abstract)
 
Séverin, S., Gratacap, MP., Lenain, N., Alvarez, L., Hollande, E., Penninger, JM., Gachet, C., Plantavid, M., Payrastre, B. (2007). Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth. J Clin Invest. 117(4):944-52 (abstract)
 
Shambharkar, PB., Blonska, M., Pappu, BP., Li, H., You, Y., Sakurai, H., Darnay, BG., Hara, H., Penninger, J., Lin, X. (2007). Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways. EMBO J. 26(7):1794-805 (abstract)
 
Skok, JA., Gisler, R., Novatchkova, M., Farmer, D., de Laat, W., Busslinger, M. (2007). Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes. Nat Immunol. 8(4):378-87 (abstract)
 
Tassi, I., Cella, M., Gilfillan, S., Turnbull, I., Diacovo, TG., Penninger, JM., Colonna, M. (2007). p110gamma and p110delta phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells. Immunity. 27(2):214-27 (abstract)
 
Uanschou, C., Siwiec, T., Pedrosa-Harand, A., Kerzendorfer, C., Sanchez-Moran, E., Novatchkova, M., Akimcheva, S., Woglar, A., Klein, F., Schlögelhofer, P. (2007). A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene. EMBO J. 26(24):5061-70 (abstract)
 
Weitzer, S., Martinez, J. (2007). The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs. Nature. 447(7141):222-6 (abstract)
 
Weitzer, S., Martinez, J. (2007). hClp1: a novel kinase revitalizes RNA metabolism. Cell Cycle. 6(17):2133-7 (abstract)
 
Wiesenberger, G., Speer, F., Haller, G., Bonnefoy, N., Schleiffer, A., Schafer, B. (2007). RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes. J Mol Biol. 367(3):681-91 (abstract)
 
Wong, DW., Oudit, GY., Reich, H., Kassiri, Z., Zhou, J., Liu, QC., Backx, PH., Penninger, JM., Herzenberg, AM., Scholey, JW. (2007). Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. Am J Pathol. 171(2):438-51 (abstract)
 
Zhang, L., Anglesio, MS., O'Sullivan, M., Zhang, F., Yang, G., Sarao, R., Mai, PN., Cronin, S., Hara, H., Melnyk, N., Li, L., Wada, T., Liu, PP., Farrar, J., Arceci, RJ., Sorensen, PH., Penninger, JM. (2007). The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers. Nat Med. 13(9):1060-9 (abstract)
 
Zuber, AM., Singer, D., Penninger, JM., Rossier, BC., Firsov, D. (2007). Increased renal responsiveness to vasopressin and enhanced V2 receptor signaling in RGS2-/- mice. J Am Soc Nephrol. 18(6):1672-8 (abstract)
 

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