December 09, 2013
Ice-cold methods decode bacterial infection systems
Bacteria have an efficient infection mechanism. They infect their host cells using syringe-like extensions, formed in large numbers during an attack. Based on the knowledge of the exact blueprint of these structures, researchers in Vienna have now revealed for the first time how the toxins infiltrate the cells. Their findings can lead to the development of new medicines for bacterial infections.
October 07, 2013
New insights into the mechanisms of cell division
Daniel Gerlich and Amalie Dick from the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences (OeAW) developed a laser microsurgery approach in live cells to study the signalling of a checkpoint that ensures correct chromosome attachment to the mitotic spindle.
October 07, 2013
Kirsten Peter Rabitsch Award 2013
On October 3, Amalie Dick received this year’s Kirsten Peter Rabitsch Award for her outstanding work on the kinetic framework of spindle assembly checkpoint signalling.
August 28, 2013
Brains on Demand
Scientists Succeed in Growing Human Brain Tissue in "Test Tubes" Vienna, Austria 26 August 2013 – Complex human brain tissue has been successfully developed in a three-dimensional culture system established in an Austrian laboratory. The method described in the current issue of NATURE allows pluripotent stem cells to develop into cerebral organoids – or "mini brains" – that consist of several discrete brain regions. Instead of using so-called patterning growth factors to achieve this, scientists at the renowned Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences (OeAW) fine-tuned growth conditions and provided a conducive environment. As a result, intrinsic cues from the stem cells guided the development towards different interdependent brain tissues. Using the "mini brains", the scientists were also able to model the development of a human neuronal disorder and identify its origin – opening up routes to long hoped-for model systems of the human brain.
August 13, 2013
Three IMBA researchers receive ERC Grants
Josef Penninger receives ERC Advanced Grant; Stefan Ameres and Kikue Tachibana-Konwalski receive ERC Starting Grants.