A RANK insider resolving the enigma of the fever chart
November 25, 2009
The mammalian system for controlling bone remodelling also regulates fever
Mammals have evolved a complex system for controlling bone remodelling. Babies require calcium for healthy bones and they obtain it from their mother’s milk. Nursing mothers release calcium from their bones, replenishing their own calcium stocks when they finish breast-feeding their young. Surprisingly, however, the same system also plays a key part in the control of fever and of female body temperature. This finding is reported in a paper in this week's issue of Nature from Josef Penninger's group at the IMBA (Institute of
Molecular Biotechnology of the Austrian Academy of Sciences) in Vienna.